STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THI1-2Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...] (359 aa)    
Predicted Functional Partners:
V4TLM9_9ROSI
Uncharacterized protein.
  
  
 
0.901
THI1
Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...]
  
  
 
0.901
V4T678_9ROSI
Uncharacterized protein.
  
  
 0.725
V4RUB9_9ROSI
ThiC-associated domain-containing protein.
  
  
 0.678
V4TLM7_9ROSI
Uncharacterized protein.
  
  
 0.674
V4TZN5_9ROSI
Uncharacterized protein; Belongs to the peptidase C1 family.
      
 0.513
V4U5S6_9ROSI
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
     
 0.483
V4UEY8_9ROSI
Uncharacterized protein; Belongs to the peptidase C1 family.
      
 0.475
V4RIC4_9ROSI
Uncharacterized protein.
   
  
 0.457
V4TC47_9ROSI
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
      
 0.457
Your Current Organism:
Citrus clementina
NCBI taxonomy Id: 85681
Other names: C. clementina, Citrus deliciosa x Citrus sinensis, clementine
Server load: low (20%) [HD]