STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF99242.1PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: mca:MCA2211 HesA/MoeB/ThiF family protein. (248 aa)    
Predicted Functional Partners:
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.997
AEF98979.1
PFAM: ThiamineS; KEGG: tgr:Tgr7_2951 molybdopterin converting factor, subunit 1.
  
 0.985
AEG01511.1
Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
   
 0.977
AEG02270.1
KEGG: mca:MCA2884 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase.
   
 0.977
AEF98980.1
PFAM: Molybdopterin biosynthesis MoaE; KEGG: tgr:Tgr7_2952 molybdopterin biosynthesis MoaE protein.
 
 0.921
AEG00794.1
Rhodanese-like protein; KEGG: bur:Bcep18194_A4015 rhodanese-related sulfurtransferase; PFAM: Rhodanese-like; SMART: Rhodanese-like.
   
 0.914
AEG01038.1
KEGG: mca:MCA1816 rhodanese-like domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like.
   
 0.864
AEG02837.1
KEGG: mta:Moth_2233 hypothetical protein.
  
 
 0.815
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.794
AEF98909.1
Mutator MutT protein; KEGG: pfo:Pfl01_4425 hypothetical protein; TIGRFAM: Mutator MutT protein; PFAM: Thiamine monophosphate synthase; NUDIX hydrolase domain.
 
  
 0.737
Your Current Organism:
Methylomonas methanica
NCBI taxonomy Id: 857087
Other names: M. methanica MC09, Methylomonas methanica MC09, Methylomonas methanica str. MC09, Methylomonas methanica strain MC09
Server load: low (28%) [HD]