Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEF99443.1KEGG: gca:Galf_2409 IstB domain-containing protein ATP-binding protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core. (249 aa)    
Predicted Functional Partners:
AEF99444.1
PFAM: Integrase, catalytic core; KEGG: hna:Hneap_1227 integrase catalytic region.
 
   0.952
AEG01137.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
 
 0.869
AEF98818.1
PFAM: Integrase, catalytic core; KEGG: hna:Hneap_1227 integrase catalytic region.
 
   0.801
AEF99945.1
PFAM: Integrase, catalytic core; KEGG: hna:Hneap_1227 integrase catalytic region.
 
   0.801
AEG01896.1
PFAM: Integrase, catalytic core; KEGG: hna:Hneap_1227 integrase catalytic region.
 
   0.801
AEG02137.1
PFAM: Integrase, catalytic core; KEGG: pol:Bpro_5321 ISPsy20, transposase IstA.
 
   0.801
AEG02143.1
PFAM: Integrase, catalytic core; KEGG: hna:Hneap_1227 integrase catalytic region.
 
   0.801
AEF99850.1
KEGG: hna:Hneap_1227 integrase catalytic region.
 
   0.794
AEG00355.1
KEGG: tau:Tola_1606 integrase catalytic region; manually curated; PFAM: Integrase, catalytic core.
  
   0.763
dnaA
Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.469
Your Current Organism:
Methylomonas methanica
NCBI taxonomy Id: 857087
Other names: M. methanica MC09, Methylomonas methanica MC09, Methylomonas methanica str. MC09, Methylomonas methanica strain MC09
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