| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEF98555.1 | AEF98556.1 | Metme_0105 | Metme_0106 | KEGG: lby:Lbys_2566 transporter, hydrophobe/amphiphile efflux-1 (hae1) family; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | KEGG: lby:Lbys_2567 efflux transporter, rnd family, mfp subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.963 |
| AEF98555.1 | AEF98884.1 | Metme_0105 | Metme_0440 | KEGG: lby:Lbys_2566 transporter, hydrophobe/amphiphile efflux-1 (hae1) family; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | KEGG: nwa:Nwat_1286 RND family efflux transporter MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.868 |
| AEF98555.1 | AEF99961.1 | Metme_0105 | Metme_1540 | KEGG: lby:Lbys_2566 transporter, hydrophobe/amphiphile efflux-1 (hae1) family; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | KEGG: rpf:Rpic12D_4296 efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.738 |
| AEF98555.1 | AEG00081.1 | Metme_0105 | Metme_1662 | KEGG: lby:Lbys_2566 transporter, hydrophobe/amphiphile efflux-1 (hae1) family; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | Efflux transporter, RND family, MFP subunit; KEGG: mca:MCA0177 hypothetical protein; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.556 |
| AEF98555.1 | AEG00082.1 | Metme_0105 | Metme_1663 | KEGG: lby:Lbys_2566 transporter, hydrophobe/amphiphile efflux-1 (hae1) family; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | KEGG: mca:MCA0176 outer membrane efflux protein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein. | 0.613 |
| AEF98556.1 | AEF98555.1 | Metme_0106 | Metme_0105 | KEGG: lby:Lbys_2567 efflux transporter, rnd family, mfp subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: lby:Lbys_2566 transporter, hydrophobe/amphiphile efflux-1 (hae1) family; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | 0.963 |
| AEF98556.1 | AEF98883.1 | Metme_0106 | Metme_0439 | KEGG: lby:Lbys_2567 efflux transporter, rnd family, mfp subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: noc:Noc_1827 hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | 0.850 |
| AEF98556.1 | AEG00080.1 | Metme_0106 | Metme_1661 | KEGG: lby:Lbys_2567 efflux transporter, rnd family, mfp subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | PFAM: Acriflavin resistance protein; KEGG: mca:MCA0178 AcrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.507 |
| AEF98556.1 | AEG00082.1 | Metme_0106 | Metme_1663 | KEGG: lby:Lbys_2567 efflux transporter, rnd family, mfp subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: mca:MCA0176 outer membrane efflux protein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein. | 0.586 |
| AEF98556.1 | macB | Metme_0106 | Metme_1869 | KEGG: lby:Lbys_2567 efflux transporter, rnd family, mfp subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Phosphonate-transporting ATPase; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.892 |
| AEF98883.1 | AEF98556.1 | Metme_0439 | Metme_0106 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: noc:Noc_1827 hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | KEGG: lby:Lbys_2567 efflux transporter, rnd family, mfp subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.850 |
| AEF98883.1 | AEF98884.1 | Metme_0439 | Metme_0440 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: noc:Noc_1827 hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | KEGG: nwa:Nwat_1286 RND family efflux transporter MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.970 |
| AEF98883.1 | AEF99961.1 | Metme_0439 | Metme_1540 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: noc:Noc_1827 hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | KEGG: rpf:Rpic12D_4296 efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.825 |
| AEF98883.1 | AEG00081.1 | Metme_0439 | Metme_1662 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: noc:Noc_1827 hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | Efflux transporter, RND family, MFP subunit; KEGG: mca:MCA0177 hypothetical protein; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.563 |
| AEF98883.1 | AEG00082.1 | Metme_0439 | Metme_1663 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: noc:Noc_1827 hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | KEGG: mca:MCA0176 outer membrane efflux protein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein. | 0.653 |
| AEF98884.1 | AEF98555.1 | Metme_0440 | Metme_0105 | KEGG: nwa:Nwat_1286 RND family efflux transporter MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: lby:Lbys_2566 transporter, hydrophobe/amphiphile efflux-1 (hae1) family; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | 0.868 |
| AEF98884.1 | AEF98883.1 | Metme_0440 | Metme_0439 | KEGG: nwa:Nwat_1286 RND family efflux transporter MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; KEGG: noc:Noc_1827 hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein. | 0.970 |
| AEF98884.1 | AEG00080.1 | Metme_0440 | Metme_1661 | KEGG: nwa:Nwat_1286 RND family efflux transporter MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | PFAM: Acriflavin resistance protein; KEGG: mca:MCA0178 AcrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.569 |
| AEF98884.1 | AEG00082.1 | Metme_0440 | Metme_1663 | KEGG: nwa:Nwat_1286 RND family efflux transporter MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | KEGG: mca:MCA0176 outer membrane efflux protein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein. | 0.706 |
| AEF98884.1 | macB | Metme_0440 | Metme_1869 | KEGG: nwa:Nwat_1286 RND family efflux transporter MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Phosphonate-transporting ATPase; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.914 |