STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG00414.1PFAM: ParB-like nuclease; SMART: ParB-like nuclease. (267 aa)    
Predicted Functional Partners:
rsmG
Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
  
  
 0.675
AEG00413.1
PFAM: DSBA oxidoreductase; KEGG: tgr:Tgr7_1053 hypothetical protein.
       0.548
AEG00347.1
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: hha:Hhal_0643 cobyrinic acid a,c-diamide synthase.
  
 
 0.545
AEG00561.1
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: hha:Hhal_2164 cobyrinic acid a,c-diamide synthase.
  
 
 0.545
AEG01442.1
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: mca:MCA1454 ParA family protein.
  
 
 0.545
AEG02410.1
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: mmw:Mmwyl1_3421 cobyrinic acid ac-diamide synthase.
  
 
 0.545
AEG02854.1
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: maq:Maqu_3884 cobyrinic acid a,c-diamide synthase.
  
 
 0.545
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.529
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.419
Your Current Organism:
Methylomonas methanica
NCBI taxonomy Id: 857087
Other names: M. methanica MC09, Methylomonas methanica MC09, Methylomonas methanica str. MC09, Methylomonas methanica strain MC09
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.