Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEG00865.1KEGG: mep:MPQ_2599 transcriptional regulator, crp/fnr family; PFAM: Cyclic nucleotide-binding; SMART: HTH transcriptional regulator, Crp; Cyclic nucleotide-binding. (236 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.568
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.554
AEG02487.1
KEGG: pol:Bpro_0721 adenylate/guanylate cyclase; PFAM: CHASE2; Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase.
  
 0.527
AEG00866.1
Hypothetical protein.
       0.512
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.509
AEF99558.1
PAS sensor protein; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF; Serine/threonine-protein kinase domain; PAS; PAC motif; Signal transduction response regulator, receiver region; TIGRFAM: PAS; KEGG: bpy:Bphyt_1683 PAS sensor protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF; Serine/threonine-protein kinase-like domain; PAS fold; PAS fold-3; Signal transduction response regulator, receiver region.
   
 
 0.501
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.499
AEG00628.1
PFAM: Glycosyltransferase 36; Putative carbohydrate binding; Glycosyltransferase 36 associated; KEGG: mms:mma_1954 cyclic beta 1-2 glucan synthetase.
  
     0.478
AEG00199.1
Miro domain protein; KEGG: cte:CT1526 Rab family protein; PFAM: MIRO-like; Toll-Interleukin receptor; SMART: Ras small GTPase, Rab type; Toll-Interleukin receptor.
    
  0.449
AEG01309.1
TIR protein; SMART: Toll-Interleukin receptor; KEGG: amr:AM1_1973 leucine-rich repeat-containing protein.
    
  0.449
Your Current Organism:
Methylomonas methanica
NCBI taxonomy Id: 857087
Other names: M. methanica MC09, Methylomonas methanica MC09, Methylomonas methanica str. MC09, Methylomonas methanica strain MC09
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