STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG02711.1KEGG: hoh:Hoch_1218 type III restriction protein res subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; ATPase, AAA+ type, core. (447 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.967
AEG00572.1
SMART: Helicase, ATP-dependent, c2 type; DEAD-like helicase, N-terminal; Helicase-like, DEXD box c2 type; KEGG: mca:MCA1991 ATP-dependent helicase, putative.
   
 0.967
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.961
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.959
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.959
AEG01077.1
SNF2-related protein; KEGG: cyn:Cyan7425_5008 non-specific serine/threonine protein kinase; PFAM: SNF2-related; DNA/RNA helicase, C-terminal; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal.
 
 
 0.828
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.794
rapA
SNF2-related protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
   
 0.777
AEG02710.1
KEGG: rso:RSc2476 hypothetical protein.
       0.773
AEF99997.1
KEGG: dar:Daro_3599 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat.
    
  0.766
Your Current Organism:
Methylomonas methanica
NCBI taxonomy Id: 857087
Other names: M. methanica MC09, Methylomonas methanica MC09, Methylomonas methanica str. MC09, Methylomonas methanica strain MC09
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