STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAAU_2415Hypothetical protein. (327 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.897
CAAU_0433
TPR repeat.
  
  
 0.792
CAAU_1184
GGDEF/response regulator receiver domain protein.
 
 
 0.779
CAAU_2320
Electron transfer subunit protein.
  
     0.757
CAAU_1082
LysM domain-containing membrane protein.
  
     0.752
CAAU_0240
Hypothetical protein.
 
  
 0.742
CAAU_1966
Hypothetical protein.
  
     0.738
CAAU_0115
DNA replication protein dnaD.
  
     0.713
CAAU_0446
Xre family DNA-binding domain and TPR-repeat-containing protein.
 
     0.707
CAAU_2242
Hypothetical protein.
  
     0.698
Your Current Organism:
Caloramator australicus
NCBI taxonomy Id: 857293
Other names: C. australicus RC3, Caloramator australicus KCTC 5601, Caloramator australicus RC3, Caloramator australicus str. RC3, Caloramator australicus strain RC3, Caloramator sp. KCTC 5601
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.