STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAAU_2494Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (267 aa)    
Predicted Functional Partners:
CAAU_2495
Stage IV sporulation protein B.
   
 0.991
CAAU_1287
RNA polymerase sporulation specific sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.910
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.910
CAAU_2240
Stage II sporulation serine phosphatase for sigma-F activation (SpoIIE).
  
  
 0.904
CAAU_0380
Stage III sporulation protein D.
  
   
 0.892
CAAU_1298
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.886
CAAU_0282
ATP-binding region, ATPase-like:Histidine kinase,HAMP region:Histidine kinase A, N-terminal.
  
  
 0.882
CAAU_1422
Two-component sensor histidine kinase.
  
  
 0.875
CAAU_2536
RNA polymerase sporulation specific sigma factor SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.873
CAAU_0872
Stage II sporulation protein required for processing of pro-sigma-E (SpoIIR).
  
   
 0.870
Your Current Organism:
Caloramator australicus
NCBI taxonomy Id: 857293
Other names: C. australicus RC3, Caloramator australicus KCTC 5601, Caloramator australicus RC3, Caloramator australicus str. RC3, Caloramator australicus strain RC3, Caloramator sp. KCTC 5601
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