STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCP1NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (692 aa)    
Predicted Functional Partners:
A0A1E3PM84
Flavodoxin-like domain-containing protein.
 
0.956
A0A1E3PDZ1
Cytochrome b5; Belongs to the cytochrome b5 family.
    
 0.872
DRE2
Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]
    
 0.837
A0A1E3PIH3
2Fe-2S iron-sulfur cluster binding domain-containing protein.
   
 0.822
A0A1E3PPL1
Phosphoadenosine phosphosulfate reductase thioredoxin.
  
 
 0.808
A0A1E3PFQ2
Adenine nucleotide alpha hydrolases-like protein.
  
 
 0.786
A0A1E3PGX8
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.784
A0A1E3PMX2
Homocysteine S-methyltransferase.
  
 0.773
A0A1E3PDM5
ER localized, heme-binding peroxidase.
    
 
 0.732
A0A1E3PEJ6
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.727
Your Current Organism:
Nadsonia fulvescens
NCBI taxonomy Id: 857566
Other names: N. fulvescens var. elongata DSM 6958, Nadsonia fulvescens var. elongata DSM 6958
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.