STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1E3PE44Uncharacterized protein. (889 aa)    
Predicted Functional Partners:
A0A1E3PGQ9
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
    
 0.875
A0A1E3PJY1
Adenine phosphoribosyltransferase.
    
 0.828
A0A1E3PIU7
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
    
 0.822
A0A1E3PMR3
Metallo-dependent phosphatase.
    
 0.820
A0A1E3PDR0
AICARFT/IMPCHase bienzyme.
  
 
  0.807
A0A1E3PNC1
Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
    
  0.802
A0A1E3PMY3
GMP synthase.
  
 
  0.801
HAM1
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.800
A0A1E3PH03
Class I glutamine amidotransferase-like protein.
    
  0.797
A0A1E3PIY7
CMP/dCMP-type deaminase domain-containing protein.
    
 0.795
Your Current Organism:
Nadsonia fulvescens
NCBI taxonomy Id: 857566
Other names: N. fulvescens var. elongata DSM 6958, Nadsonia fulvescens var. elongata DSM 6958
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