A0A1E3PJ67 protein (Nadsonia fulvescens) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A1E3PJ67

Uncharacterized protein. (201 aa)

Predicted Functional Partners:

A0A1E3PTJ0

0.684

A0A1E3PDW3

0.671

A0A1E3PGB5

0.671

A0A1E3PH07

0.648

A0A1E3PR61

0.648

A0A1E3PGG5

0.647

A0A1E3PPW3

0.647

A0A1E3PI64

0.646

A0A1E3PNJ9

0.646

A0A1E3PSB3

0.646

Your Current Organism:

Nadsonia fulvescens

NCBI taxonomy Id: 857566
Other names: N. fulvescens var. elongata DSM 6958, Nadsonia fulvescens var. elongata DSM 6958

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1E3PDW3	A0A1E3PJ67	Uncharacterized protein.	Uncharacterized protein.	0.671
A0A1E3PGB5	A0A1E3PJ67	Uncharacterized protein.	Uncharacterized protein.	0.671
A0A1E3PGG5	A0A1E3PH07	Uncharacterized protein.	Translational machinery component.	0.999
A0A1E3PGG5	A0A1E3PJ67	Uncharacterized protein.	Uncharacterized protein.	0.647
A0A1E3PGG5	A0A1E3PNJ9	Uncharacterized protein.	Ribosomal protein S16.	0.999
A0A1E3PGG5	A0A1E3PPW3	Uncharacterized protein.	Nucleoside diphosphate kinase.	0.994
A0A1E3PGG5	A0A1E3PR61	Uncharacterized protein.	30S ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family.	0.999
A0A1E3PGG5	A0A1E3PSB3	Uncharacterized protein.	Uncharacterized protein.	0.999
A0A1E3PH07	A0A1E3PGG5	Translational machinery component.	Uncharacterized protein.	0.999
A0A1E3PH07	A0A1E3PJ67	Translational machinery component.	Uncharacterized protein.	0.648
A0A1E3PH07	A0A1E3PNJ9	Translational machinery component.	Ribosomal protein S16.	0.999
A0A1E3PH07	A0A1E3PPW3	Translational machinery component.	Nucleoside diphosphate kinase.	0.990
A0A1E3PH07	A0A1E3PR61	Translational machinery component.	30S ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family.	0.999
A0A1E3PH07	A0A1E3PSB3	Translational machinery component.	Uncharacterized protein.	0.999
A0A1E3PI64	A0A1E3PJ67	TPR-like protein.	Uncharacterized protein.	0.646
A0A1E3PJ67	A0A1E3PDW3	Uncharacterized protein.	Uncharacterized protein.	0.671
A0A1E3PJ67	A0A1E3PGB5	Uncharacterized protein.	Uncharacterized protein.	0.671
A0A1E3PJ67	A0A1E3PGG5	Uncharacterized protein.	Uncharacterized protein.	0.647
A0A1E3PJ67	A0A1E3PH07	Uncharacterized protein.	Translational machinery component.	0.648
A0A1E3PJ67	A0A1E3PI64	Uncharacterized protein.	TPR-like protein.	0.646

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

30

average node degree:

5.45

avg. local clustering coefficient:

0.826

expected number of edges:

11

PPI enrichment p-value:

3.13e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006836

Neurotransmitter transport

7 of 137

2.03

3.96

8.35e-10

GO:0098700

Neurotransmitter loading into synaptic vesicle

4 of 10

2.92

3.92

6.00e-08

GO:0099504

Synaptic vesicle cycle

6 of 127

2.0

3.25

6.00e-08

GO:0001505

Regulation of neurotransmitter levels

5 of 178

1.77

2.1

1.79e-05

GO:0017156

Calcium-ion regulated exocytosis

3 of 42

2.18

1.57

0.0010

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015495

Gamma-aminobutyric acid:proton symporter activity

3 of 3

3.32

2.97

4.36e-06

GO:0015187

Glycine transmembrane transporter activity

3 of 6

3.02

2.77

9.14e-06

GO:0015294

Solute:cation symporter activity

4 of 132

1.8

1.79

0.00014

GO:0016413

O-acetyltransferase activity

2 of 12

2.54

1.35

0.0034

GO:0042910

Xenobiotic transmembrane transporter activity

2 of 25

2.22

1.1

0.0089

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043679

Axon terminus

5 of 56

2.27

3.78

2.09e-08

GO:0051286

Cell tip

3 of 3

3.32

3.61

2.89e-07

GO:0048786

Presynaptic active zone

5 of 70

2.18

3.6

3.02e-08

GO:0044292

Dendrite terminus

3 of 8

2.9

3.18

1.47e-06

GO:0098793

Presynapse

8 of 405

1.62

2.93

9.78e-10

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:23104

Mixed, incl. Norepinephrine Neurotransmitter Release Cycle, and Vesicle fusion to plasma membrane

8 of 65

2.41

6.74

5.33e-15

CL:23106

Norepinephrine Neurotransmitter Release Cycle, and Vesicle fusion to plasma membrane

5 of 58

2.26

3.74

2.36e-08

CL:23108

Mixed, incl. Vesicle fusion to plasma membrane, and Serotonin Neurotransmitter Release Cycle

3 of 32

2.29

1.96

0.00019

CL:23162

Mixed, incl. Acetate ester transmembrane transporter activity, and Cell tip

2 of 5

2.92

1.56

0.0015

CL:27951

Acyltransferase ChoActase/COT/CPT, and Glycerophosphodiester phosphodiesterase domain

2 of 12

2.54

1.21

0.0060

(more ...)

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-112310

Neurotransmitter release cycle

8 of 112

2.18

5.63

1.15e-13

MAP-888590

GABA synthesis, release, reuptake and degradation

5 of 42

2.4

4.11

7.17e-09

MAP-264642

Acetylcholine Neurotransmitter Release Cycle

4 of 37

2.36

3.09

9.36e-07

MAP-112315

Transmission across Chemical Synapses

8 of 454

1.57

2.7

3.18e-09

MAP-112316

Neuronal System

8 of 696

1.38

2.05

4.59e-08

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044292

Dendrite terminus

3 of 9

2.84

2.75

8.99e-06

GOCC:0098793

Presynapse

6 of 197

1.81

2.73

2.93e-07

GOCC:0030285

Integral component of synaptic vesicle membrane

3 of 14

2.65

2.53

2.08e-05

GOCC:0030658

Transport vesicle membrane

4 of 89

1.97

2.22

2.40e-05

GOCC:0045202

Synapse

7 of 545

1.43

1.93

1.00e-06

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01490

Transmembrane amino acid transporter protein

3 of 15

2.62

2.07

0.00015

PF02318

FYVE-type zinc finger

2 of 12

2.54

0.91

0.0218

PF00755

Choline/Carnitine o-acyltransferase

2 of 12

2.54

0.91

0.0218

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR013057

Amino acid transporter, transmembrane domain

3 of 17

2.57

1.73

0.00066

IPR004734

Multidrug resistance protein

2 of 4

3.02

1.08

0.0111

IPR039032

Rim-like

2 of 7

2.78

0.97

0.0177

IPR042231

Choline/Carnitine o-acyltransferase, domain 2

2 of 11

2.58

0.85

0.0288

IPR041282

FYVE-type zinc finger

2 of 12

2.54

0.85

0.0288

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (14%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About