STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1E3PNU9Uncharacterized protein. (1064 aa)    
Predicted Functional Partners:
A0A1E3PNM9
Rad51 N-terminal domain-like protein.
  
 
 0.946
A0A1E3PQ44
DNA repair protein, SNF2 family.
  
 
0.928
A0A1E3PF61
ERCC4 domain-containing protein.
   
 0.835
A0A1E3PIZ2
PIN domain-like protein.
   
 0.812
A0A1E3PM01
Actin-like ATPase domain-containing protein; Belongs to the actin family.
    
 0.784
A0A1E3PIX6
P-loop containing nucleoside triphosphate hydrolase protein.
   
 
 0.782
A0A1E3PHV6
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 0.779
A0A1E3PG05
DNA-directed RNA polymerases I.
   
 0.774
A0A1E3PL74
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.764
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.750
Your Current Organism:
Nadsonia fulvescens
NCBI taxonomy Id: 857566
Other names: N. fulvescens var. elongata DSM 6958, Nadsonia fulvescens var. elongata DSM 6958
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