| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CVAR_0650 | cysQ | CVAR_0650 | CVAR_0652 | Glutaredoxin and related proteins. | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 0.729 |
| CVAR_0650 | folA | CVAR_0650 | CVAR_3047 | Glutaredoxin and related proteins. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.828 |
| CVAR_0650 | thyA | CVAR_0650 | CVAR_0651 | Glutaredoxin and related proteins. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.830 |
| CVAR_0653 | cysQ | CVAR_0653 | CVAR_0652 | Putative amine oxidase; Predicted NAD/FAD-binding protein. | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 0.470 |
| CVAR_1578 | cysQ | CVAR_1578 | CVAR_0652 | Hypothetical protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 0.481 |
| cysD | cysH | CVAR_0451 | CVAR_3042 | Sulfate adenylyltransferase subunit 2; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. | Adenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.988 |
| cysD | cysN | CVAR_0451 | CVAR_0452 | Sulfate adenylyltransferase subunit 2; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
| cysD | cysQ | CVAR_0451 | CVAR_0652 | Sulfate adenylyltransferase subunit 2; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 0.928 |
| cysH | cysD | CVAR_3042 | CVAR_0451 | Adenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | Sulfate adenylyltransferase subunit 2; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. | 0.988 |
| cysH | cysN | CVAR_3042 | CVAR_0452 | Adenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.997 |
| cysH | cysQ | CVAR_3042 | CVAR_0652 | Adenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 0.947 |
| cysN | cysD | CVAR_0452 | CVAR_0451 | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Sulfate adenylyltransferase subunit 2; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. | 0.999 |
| cysN | cysH | CVAR_0452 | CVAR_3042 | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Adenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.997 |
| cysN | cysQ | CVAR_0452 | CVAR_0652 | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 0.932 |
| cysQ | CVAR_0650 | CVAR_0652 | CVAR_0650 | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Glutaredoxin and related proteins. | 0.729 |
| cysQ | CVAR_0653 | CVAR_0652 | CVAR_0653 | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Putative amine oxidase; Predicted NAD/FAD-binding protein. | 0.470 |
| cysQ | CVAR_1578 | CVAR_0652 | CVAR_1578 | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Hypothetical protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 0.481 |
| cysQ | cysD | CVAR_0652 | CVAR_0451 | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Sulfate adenylyltransferase subunit 2; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. | 0.928 |
| cysQ | cysH | CVAR_0652 | CVAR_3042 | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Adenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.947 |
| cysQ | cysN | CVAR_0652 | CVAR_0452 | Inositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.932 |