STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysQInositol-1-monophosphatase family protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (335 aa)    
Predicted Functional Partners:
cysH
Adenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
  
 
 0.947
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
 
 0.932
cysD
Sulfate adenylyltransferase subunit 2; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.
  
 
 0.928
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
    0.807
CVAR_0650
Glutaredoxin and related proteins.
 
     0.729
folA
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
     
 0.706
orn
Hypothetical protein; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
      
 0.507
putA
NAD-dependent aldehyde dehydrogenases.
   
  
 0.501
CVAR_1578
Hypothetical protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.
     
 0.481
CVAR_0653
Putative amine oxidase; Predicted NAD/FAD-binding protein.
       0.470
Your Current Organism:
Corynebacterium variabile
NCBI taxonomy Id: 858619
Other names: C. variabile DSM 44702, Corynebacterium variabile CIP 107183, Corynebacterium variabile DSM 44702, Corynebacterium variabile LMG S-19265, Corynebacterium variabile str. DSM 44702, Corynebacterium variabile strain DSM 44702
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