| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CVAR_1100 | CVAR_1102 | CVAR_1100 | CVAR_1102 | ABC-type oligopeptide transport system, ATPase component. | Hypothetical protein. | 0.533 |
| CVAR_1100 | glnE | CVAR_1100 | CVAR_1098 | ABC-type oligopeptide transport system, ATPase component. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.576 |
| CVAR_1100 | hmuO | CVAR_1100 | CVAR_1101 | ABC-type oligopeptide transport system, ATPase component. | Heme oxygenase. | 0.754 |
| CVAR_1100 | hmuU | CVAR_1100 | CVAR_1099 | ABC-type oligopeptide transport system, ATPase component. | ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.981 |
| CVAR_1102 | CVAR_1100 | CVAR_1102 | CVAR_1100 | Hypothetical protein. | ABC-type oligopeptide transport system, ATPase component. | 0.533 |
| CVAR_1102 | CVAR_1103 | CVAR_1102 | CVAR_1103 | Hypothetical protein. | Hypothetical protein; NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. | 0.568 |
| CVAR_1102 | glnE | CVAR_1102 | CVAR_1098 | Hypothetical protein. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.412 |
| CVAR_1102 | hmuO | CVAR_1102 | CVAR_1101 | Hypothetical protein. | Heme oxygenase. | 0.727 |
| CVAR_1102 | hmuU | CVAR_1102 | CVAR_1099 | Hypothetical protein. | ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.434 |
| CVAR_1103 | CVAR_1102 | CVAR_1103 | CVAR_1102 | Hypothetical protein; NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. | Hypothetical protein. | 0.568 |
| CVAR_1103 | hmuO | CVAR_1103 | CVAR_1101 | Hypothetical protein; NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. | Heme oxygenase. | 0.514 |
| glnE | CVAR_1100 | CVAR_1098 | CVAR_1100 | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | ABC-type oligopeptide transport system, ATPase component. | 0.576 |
| glnE | CVAR_1102 | CVAR_1098 | CVAR_1102 | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | Hypothetical protein. | 0.412 |
| glnE | hmuO | CVAR_1098 | CVAR_1101 | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | Heme oxygenase. | 0.534 |
| glnE | hmuU | CVAR_1098 | CVAR_1099 | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.551 |
| hmuO | CVAR_1100 | CVAR_1101 | CVAR_1100 | Heme oxygenase. | ABC-type oligopeptide transport system, ATPase component. | 0.754 |
| hmuO | CVAR_1102 | CVAR_1101 | CVAR_1102 | Heme oxygenase. | Hypothetical protein. | 0.727 |
| hmuO | CVAR_1103 | CVAR_1101 | CVAR_1103 | Heme oxygenase. | Hypothetical protein; NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. | 0.514 |
| hmuO | glnE | CVAR_1101 | CVAR_1098 | Heme oxygenase. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.534 |
| hmuO | hmuU | CVAR_1101 | CVAR_1099 | Heme oxygenase. | ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.558 |