STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
impAArchaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (341 aa)    
Predicted Functional Partners:
hisF
Imidazoleglycerol-phosphate synthase cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.981
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Imidazoleglycerol-phosphate synthase.
  
  
 0.979
CVAR_1578
Hypothetical protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.
  
  
  0.976
ino
Myo-inositol-1-phosphate synthase.
  
 
 0.959
CVAR_1208
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family.
  
  
 0.891
hisH
Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.884
hisB
Imidazoleglycerol-phosphate dehydratase.
  
  
 0.785
CVAR_0687
Hypothetical protein; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.
  
   
 0.765
CVAR_1210
Putative membrane protein.
     
 0.723
CVAR_1203
Putative membrane protein; Permeases of the major facilitator superfamily.
     
 0.708
Your Current Organism:
Corynebacterium variabile
NCBI taxonomy Id: 858619
Other names: C. variabile DSM 44702, Corynebacterium variabile CIP 107183, Corynebacterium variabile DSM 44702, Corynebacterium variabile LMG S-19265, Corynebacterium variabile str. DSM 44702, Corynebacterium variabile strain DSM 44702
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