STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CVAR_1678Hypothetical protein; Lhr-like helicases. (742 aa)    
Predicted Functional Partners:
CVAR_1677
Hypothetical protein; Uroporphyrinogen-III decarboxylase.
 
     0.794
CVAR_1675
Putative phage resistance protein.
 
     0.792
CVAR_1676
Putative phage resistance protein.
 
     0.792
CVAR_1674
Hypothetical protein; Type II restriction enzyme, methylase subunits.
 
     0.790
CVAR_1673
Serine/threonine protein kinase.
 
     0.779
CVAR_0676
Hypothetical protein; Formamidopyrimidine-DNA glycosylase.
  
  
 0.709
CVAR_0546
Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.
  
  
 0.575
CVAR_1136
Hypothetical protein; DNA polymerase III, alpha subunit (gram- positive type).
  
  
 0.526
radA
DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
    0.497
fpg2
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.454
Your Current Organism:
Corynebacterium variabile
NCBI taxonomy Id: 858619
Other names: C. variabile DSM 44702, Corynebacterium variabile CIP 107183, Corynebacterium variabile DSM 44702, Corynebacterium variabile LMG S-19265, Corynebacterium variabile str. DSM 44702, Corynebacterium variabile strain DSM 44702
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