STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CVAR_1762Hypothetical protein; DNA polymerase III, alpha subunit (gram- positive type). (214 aa)    
Predicted Functional Partners:
CVAR_1763
Predicted signal-transduction protein containing cAMP-binding and CBS domains.
 
    0.963
dnaX
DNA polymerase III, gamma/tau subunits.
   
 0.960
CVAR_1136
Hypothetical protein; DNA polymerase III, alpha subunit (gram- positive type).
 
  
 0.959
dnaN
DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.958
CVAR_0846
Hypothetical protein.
  
 0.958
dnaE
DNA polymerase III, alpha subunit.
   
 0.957
holA
DNA polymerase III, delta subunit.
    
 0.936
CVAR_1804
Hypothetical protein; DNA polymerase III, alpha subunit (gram- positive type).
  
  
  0.919
holB
DNA polymerase III delta subunit; ATPase involved in DNA replication.
   
 0.917
dnaQ
DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
     
  0.900
Your Current Organism:
Corynebacterium variabile
NCBI taxonomy Id: 858619
Other names: C. variabile DSM 44702, Corynebacterium variabile CIP 107183, Corynebacterium variabile DSM 44702, Corynebacterium variabile LMG S-19265, Corynebacterium variabile str. DSM 44702, Corynebacterium variabile strain DSM 44702
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.