| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gnd | pgk | CVAR_1307 | CVAR_1482 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.611 |
| gnd | rpe | CVAR_1307 | CVAR_3043 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.947 |
| gnd | rpi | CVAR_1307 | CVAR_0823 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Ribose 5-phosphate isomerase RpiB. | 0.916 |
| gnd | tkt | CVAR_1307 | CVAR_1474 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Transketolase; Belongs to the transketolase family. | 0.844 |
| gnd | zwf | CVAR_1307 | CVAR_1476 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.996 |
| metK | pgk | CVAR_1500 | CVAR_1482 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.700 |
| metK | ribD | CVAR_1500 | CVAR_1492 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.597 |
| metK | rpe | CVAR_1500 | CVAR_3043 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.766 |
| metK | tpi | CVAR_1500 | CVAR_1481 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.699 |
| pgk | gnd | CVAR_1482 | CVAR_1307 | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.611 |
| pgk | metK | CVAR_1482 | CVAR_1500 | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.700 |
| pgk | ptsF | CVAR_1482 | CVAR_2115 | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Phosphotransferase system, fructose-specific IIC component. | 0.671 |
| pgk | ribD | CVAR_1482 | CVAR_1492 | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.553 |
| pgk | rpe | CVAR_1482 | CVAR_3043 | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.829 |
| pgk | tkt | CVAR_1482 | CVAR_1474 | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Transketolase; Belongs to the transketolase family. | 0.732 |
| pgk | tpi | CVAR_1482 | CVAR_1481 | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.999 |
| pgk | zwf | CVAR_1482 | CVAR_1476 | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.497 |
| ptsF | pgk | CVAR_2115 | CVAR_1482 | Phosphotransferase system, fructose-specific IIC component. | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.671 |
| ptsF | rpe | CVAR_2115 | CVAR_3043 | Phosphotransferase system, fructose-specific IIC component. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.846 |
| ptsF | rpi | CVAR_2115 | CVAR_0823 | Phosphotransferase system, fructose-specific IIC component. | Ribose 5-phosphate isomerase RpiB. | 0.785 |