STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H6CAJ5_EXODNBH4_2 domain-containing protein. (486 aa)    
Predicted Functional Partners:
H6CAB5_EXODN
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
    
 0.552
H6C377_EXODN
Xanthine dehydrogenase.
  
 
 0.545
H6BRN3_EXODN
Adenine phosphoribosyltransferase.
     
 0.524
H6C346_EXODN
NADPH:adrenodoxin oxidoreductase, mitochondrial.
  
 
  0.488
H6C8A9_EXODN
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
   
  0.485
H6C3X3_EXODN
NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial.
    
 0.467
H6BM03_EXODN
Pribosyltran domain-containing protein.
     
 0.450
H6BSG2_EXODN
NADH pyrophosphatase.
    
  0.441
Your Current Organism:
Exophiala dermatitidis
NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656
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