STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDB27204.1leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (852 aa)    
Predicted Functional Partners:
MetG
methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
0.987
SDB23166.1
phenylalanyl-tRNA synthetase beta subunit.
  
  
 0.973
SDB03458.1
Isoleucyl-tRNA synthetase.
 
0.928
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 0.926
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
 
 0.897
RlmB
23S rRNA (guanosine2251-2'-O)-methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
   0.884
SDB12599.1
arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.859
SDB05273.1
valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
0.825
recA
Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
 
 0.825
TsaD
N6-L-threonylcarbamoyladenine synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
   
 
 0.807
Your Current Organism:
Fusobacterium necrophorum
NCBI taxonomy Id: 859
Other names: ATCC 25286, Acinomyces pseudonecrophorus, Actinomyces necrophorus, Bacillus necrophorus, Bacillus necroseos, Bacillus necrosus, Bacterium necrophorum, Bacteroides necrophorus, CCUG 9994, CIP 104559, Corynebacterium necrophorum, DSM 21784, F. necrophorum, Fusibacterium necrophorum, Fusiformis hemolyticus, Fusiformis necrophorus, JCM 3718, NCTC 13726, Necrobacterium necrophorus, Proactinomyces necrophorus, Sphaerophorus necrophorus, Sphaerophorus pseudonecrophorus, Streptothrix necrophorus, Streptothrix necuphtora, VPI 2891
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