node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LpxB | LpxK | SAMN02983009_00175 | SAMN02983009_01366 | lipid-A-disaccharide synthase; Belongs to the LpxB family. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.998 |
LpxB | SDB15017.1 | SAMN02983009_00175 | SAMN02983009_00703 | lipid-A-disaccharide synthase; Belongs to the LpxB family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.767 |
LpxB | SDB28864.1 | SAMN02983009_00175 | SAMN02983009_01398 | lipid-A-disaccharide synthase; Belongs to the LpxB family. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.774 |
LpxB | SDB39099.1 | SAMN02983009_00175 | SAMN02983009_01874 | lipid-A-disaccharide synthase; Belongs to the LpxB family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 0.451 |
LpxB | kdsA | SAMN02983009_00175 | SAMN02983009_02307 | lipid-A-disaccharide synthase; Belongs to the LpxB family. | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.857 |
LpxB | kdsB | SAMN02983009_00175 | SAMN02983009_01250 | lipid-A-disaccharide synthase; Belongs to the LpxB family. | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.809 |
LpxB | lpxA | SAMN02983009_00175 | SAMN02983009_00177 | lipid-A-disaccharide synthase; Belongs to the LpxB family. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.997 |
LpxB | lpxC | SAMN02983009_00175 | SAMN02983009_00179 | lipid-A-disaccharide synthase; Belongs to the LpxB family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.972 |
LpxB | lpxD | SAMN02983009_00175 | SAMN02983009_00301 | lipid-A-disaccharide synthase; Belongs to the LpxB family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.996 |
LpxK | LpxB | SAMN02983009_01366 | SAMN02983009_00175 | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | lipid-A-disaccharide synthase; Belongs to the LpxB family. | 0.998 |
LpxK | SDB15017.1 | SAMN02983009_01366 | SAMN02983009_00703 | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.976 |
LpxK | SDB28864.1 | SAMN02983009_01366 | SAMN02983009_01398 | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.849 |
LpxK | SDB39099.1 | SAMN02983009_01366 | SAMN02983009_01874 | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 0.502 |
LpxK | kdsA | SAMN02983009_01366 | SAMN02983009_02307 | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.893 |
LpxK | kdsB | SAMN02983009_01366 | SAMN02983009_01250 | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.842 |
LpxK | lpxA | SAMN02983009_01366 | SAMN02983009_00177 | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.946 |
LpxK | lpxC | SAMN02983009_01366 | SAMN02983009_00179 | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.908 |
LpxK | lpxD | SAMN02983009_01366 | SAMN02983009_00301 | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.948 |
SDB15017.1 | LpxB | SAMN02983009_00703 | SAMN02983009_00175 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Belongs to the LpxB family. | 0.767 |
SDB15017.1 | LpxK | SAMN02983009_00703 | SAMN02983009_01366 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.976 |