STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDB30213.1Nucleobase:cation symporter-2, NCS2 family. (435 aa)    
Predicted Functional Partners:
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 0.973
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.734
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.704
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.684
carA
Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family.
  
  
 0.680
carB
Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
  
  
 0.675
SDB24450.1
Phosphoribosylformylglycinamidine synthase.
  
  
 0.668
pyrD
Dihydroorotate dehydrogenase (NAD+) catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
  
 0.580
SDB12698.1
Dihydroorotase.
  
  
 0.567
SDB37579.1
Beta-aspartyl-dipeptidase (metallo-type); Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
  
  
 0.567
Your Current Organism:
Fusobacterium necrophorum
NCBI taxonomy Id: 859
Other names: ATCC 25286, Acinomyces pseudonecrophorus, Actinomyces necrophorus, Bacillus necrophorus, Bacillus necroseos, Bacillus necrosus, Bacterium necrophorum, Bacteroides necrophorus, CCUG 9994, CIP 104559, Corynebacterium necrophorum, DSM 21784, F. necrophorum, Fusibacterium necrophorum, Fusiformis hemolyticus, Fusiformis necrophorus, JCM 3718, NCTC 13726, Necrobacterium necrophorus, Proactinomyces necrophorus, Sphaerophorus necrophorus, Sphaerophorus pseudonecrophorus, Streptothrix necrophorus, Streptothrix necuphtora, VPI 2891
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.