SDB40919.1 protein (Fusobacterium necrophorum)

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SDB40919.1

Site-specific recombinase XerD. (374 aa)

Predicted Functional Partners:

SDB40903.1

0.528

SDB40935.1

0.486

SDB40946.1

0.465

Your Current Organism:

Fusobacterium necrophorum

NCBI taxonomy Id: 859
Other names: ATCC 25286, Acinomyces pseudonecrophorus, Actinomyces necrophorus, Bacillus necrophorus, Bacillus necroseos, Bacillus necrosus, Bacterium necrophorum, Bacteroides necrophorus, CCUG 9994, CIP 104559, Corynebacterium necrophorum, DSM 21784, F. necrophorum, Fusibacterium necrophorum, Fusiformis hemolyticus, Fusiformis necrophorus, JCM 3718, NCTC 13726, Necrobacterium necrophorus, Proactinomyces necrophorus, Sphaerophorus necrophorus, Sphaerophorus pseudonecrophorus, Streptothrix necrophorus, Streptothrix necuphtora, VPI 2891

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDB40903.1	SDB40919.1	SAMN02983009_01956	SAMN02983009_01957	Hypothetical protein.	Site-specific recombinase XerD.	0.528
SDB40919.1	SDB40903.1	SAMN02983009_01957	SAMN02983009_01956	Site-specific recombinase XerD.	Hypothetical protein.	0.528
SDB40919.1	SDB40935.1	SAMN02983009_01957	SAMN02983009_01958	Site-specific recombinase XerD.	Hypothetical protein.	0.486
SDB40919.1	SDB40946.1	SAMN02983009_01957	SAMN02983009_01959	Site-specific recombinase XerD.	Helix-turn-helix domain-containing protein.	0.465
SDB40935.1	SDB40919.1	SAMN02983009_01958	SAMN02983009_01957	Hypothetical protein.	Site-specific recombinase XerD.	0.486
SDB40935.1	SDB40946.1	SAMN02983009_01958	SAMN02983009_01959	Hypothetical protein.	Helix-turn-helix domain-containing protein.	0.737
SDB40946.1	SDB40919.1	SAMN02983009_01959	SAMN02983009_01957	Helix-turn-helix domain-containing protein.	Site-specific recombinase XerD.	0.465
SDB40946.1	SDB40935.1	SAMN02983009_01959	SAMN02983009_01958	Helix-turn-helix domain-containing protein.	Hypothetical protein.	0.737

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

26

PPI enrichment p-value:

3.23e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006633

Fatty acid biosynthetic process

8 of 17

2.07

4.9

2.49e-12

GO:2001295

malonyl-CoA biosynthetic process

2 of 4

2.1

0.96

0.0159

GO:0044281

Small molecule metabolic process

9 of 458

0.69

0.58

0.00035

GO:0071704

Organic substance metabolic process

11 of 1212

0.36

0.29

0.0098

GO:0044238

Primary metabolic process

10 of 999

0.4

0.29

0.0198

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004312

Fatty acid synthase activity

4 of 7

2.16

2.31

2.74e-05

GO:0016747

Acyltransferase activity, transferring groups other than amino-acyl groups

5 of 41

1.48

1.52

0.00014

GO:0000036

Acyl carrier activity

2 of 2

2.4

1.02

0.0133

GO:0003989

acetyl-CoA carboxylase activity

2 of 3

2.22

1.01

0.0133

GO:0016743

Carboxyl- or carbamoyltransferase activity

2 of 5

2.0

0.93

0.0169

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009317

acetyl-CoA carboxylase complex

2 of 4

2.1

1.07

0.0096

GO:0005737

Cytoplasm

11 of 997

0.44

0.36

0.0020

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1342

Fatty acid metabolism, and Alpha/beta hydrolase fold

7 of 13

2.13

4.56

6.41e-11

CL:1345

Fatty acid metabolism

4 of 8

2.1

2.57

5.86e-06

CL:1199

Mixed, incl. Pyruvate metabolism, and Citrate cycle (TCA cycle)

8 of 91

1.34

1.94

6.37e-08

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pace01212

Fatty acid metabolism

6 of 10

2.18

4.29

5.66e-10

pace00061

Fatty acid biosynthesis

6 of 10

2.18

4.29

5.66e-10

pace00780

Biotin metabolism

4 of 11

1.96

2.46

5.80e-06

pace01100

Metabolic pathways

9 of 530

0.63

0.53

0.00035

pace01110

Biosynthesis of secondary metabolites

5 of 249

0.7

0.42

0.0351

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009317

acetyl-CoA carboxylase complex

2 of 4

2.1

0.84

0.0276

GOCC:0005737

Cytoplasm

10 of 756

0.52

0.39

0.0054

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0275

Fatty acid biosynthesis

5 of 9

2.14

3.49

4.57e-08

KW-0444

Lipid biosynthesis

6 of 21

1.85

3.07

4.33e-08

KW-0596

Phosphopantetheine

2 of 2

2.4

1.33

0.0035

KW-0012

Acyltransferase

3 of 24

1.5

1.05

0.0044

KW-0963

Cytoplasm

6 of 253

0.77

0.56

0.0057

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01039

Carboxyl transferase domain

2 of 2

2.4

0.77

0.0390

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