node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MHF_1551 | metK | MHF_1551 | MHF_1583 | Putative methyltransferase. | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.640 |
MHF_1551 | nfo | MHF_1551 | MHF_0266 | Putative methyltransferase. | Putative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.620 |
MHF_1551 | rpmH | MHF_1551 | MHF_1616 | Putative methyltransferase. | 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.651 |
MHF_1551 | trkA | MHF_1551 | MHF_0054 | Putative methyltransferase. | Potassium uptake protein TrkA. | 0.613 |
dnaJ | guaB | MHF_0050 | MHF_0056 | Chaperone prtein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...] | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.565 |
dnaJ | metK | MHF_0050 | MHF_1583 | Chaperone prtein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...] | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.698 |
dnaJ | potB | MHF_0050 | MHF_1587 | Chaperone prtein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...] | Spermidine/putrescine transport system permease PotB. | 0.614 |
dnaJ | rpmH | MHF_0050 | MHF_1616 | Chaperone prtein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...] | 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.580 |
dnaJ | trkA | MHF_0050 | MHF_0054 | Chaperone prtein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...] | Potassium uptake protein TrkA. | 0.620 |
guaB | dnaJ | MHF_0056 | MHF_0050 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Chaperone prtein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...] | 0.565 |
guaB | ktrB | MHF_0056 | MHF_0055 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Potassium uptake protein KtrB. | 0.807 |
guaB | trkA | MHF_0056 | MHF_0054 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Potassium uptake protein TrkA. | 0.680 |
ktrB | guaB | MHF_0055 | MHF_0056 | Potassium uptake protein KtrB. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.807 |
ktrB | trkA | MHF_0055 | MHF_0054 | Potassium uptake protein KtrB. | Potassium uptake protein TrkA. | 0.999 |
metK | MHF_1551 | MHF_1583 | MHF_1551 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Putative methyltransferase. | 0.640 |
metK | dnaJ | MHF_1583 | MHF_0050 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Chaperone prtein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...] | 0.698 |
metK | potB | MHF_1583 | MHF_1587 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Spermidine/putrescine transport system permease PotB. | 0.931 |
metK | rpmH | MHF_1583 | MHF_1616 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.620 |
metK | trkA | MHF_1583 | MHF_0054 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Potassium uptake protein TrkA. | 0.640 |
nfo | MHF_1551 | MHF_0266 | MHF_1551 | Putative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | Putative methyltransferase. | 0.620 |