STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cheV1Chemotaxis protein (cheV); Plays an essential role in chemotaxis signal transduction system in order to colonize the host stomach. May act as a phosphate sink to control the flow of phosphate to CheAY. (321 aa)    
Predicted Functional Partners:
cheAY
Histidine kinase (cheA); Member of the two-component regulatory system CheAY/CheY that regulates chemotaxis and colonization of the gastric mucosa. Functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to the conserved aspartic acid residue in the regulatory domain of CheY. In turn, phosphorylated CheY (CheY-P) interacts with the flagellar motor protein FliM to cause clockwise flagellar rotation and bacterial reversals, as opposed to straight swimming when CheY is not phosphorylated (By similarity).
 
 0.999
HP_0082
Methyl-accepting chemotaxis transducer (tlpC); Similar to GB:Z34005 SP:P39209 GB:D30762 PID:496484 PID:710635 percent identity: 27.96; identified by sequence similarity; putative.
 
 0.998
HP_0103
Methyl-accepting chemotaxis protein (tlpB); Similar to GB:L29189 SP:P39217 PID:459691 GB:AL009126 percent identity: 30.71; identified by sequence similarity; putative.
 
 0.998
HP_1030
fliY protein (fliY); Similar to GB:M86738 SP:P24073 PID:142926 PID:551704 GB:AL009126 percent identity: 29.27; identified by sequence similarity; putative.
  
 
 0.995
HP_0099
Methyl-accepting chemotaxis protein (tlpA); Similar to GB:L29189 SP:P39216 PID:459689 GB:AL009126 percent identity: 32.81; identified by sequence similarity; putative.
 
 0.994
HP_0599
Hemolysin secretion protein precursor (hylB); Similar to SP:P15492 GB:X16945 PID:48362 PID:2190531 percent identity: 45.39; identified by sequence similarity; putative.
 
 0.994
cheV3
Chemotaxis protein (cheV); Plays a role in chemotaxis signal transduction system in order to colonize the host stomach. May act as a phosphate sink to control the flow of phosphate to CheAY.
 
0.991
cheV2
Chemotaxis protein (cheV); Plays a role in chemotaxis signal transduction system in order to colonize the host stomach. May act as a phosphate sink to control the flow of phosphate to CheAY.
 
0.988
cheW
Purine-binding chemotaxis protein (cheW); Plays an essential role in chemotaxis signal transduction system in order to colonize the host stomach.
 
 0.984
flhF
Flagellar biosynthesis protein (flhF); Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum (By similarity); Belongs to the GTP-binding SRP family.
  
 
 0.976
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.