node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
infC | rplC | HP_0124 | HP_1319 | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.911 |
infC | rplK | HP_0124 | HP_1202 | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Ribosomal protein L11 (rpl11); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.912 |
infC | rplO | HP_0124 | HP_1301 | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Ribosomal protein L15 (rpl15); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.832 |
infC | rplT | HP_0124 | HP_0126 | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Ribosomal protein L20 (rpl20); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | 0.998 |
infC | rplV | HP_0124 | HP_1314 | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Ribosomal protein L22 (rpl22); This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.896 |
infC | rpmF | HP_0124 | HP_0200 | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Ribosomal protein L32 (rpl32); Similar to SP:P07840 percent identity: 41.67; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL32 family. | 0.915 |
infC | rpsK | HP_0124 | HP_1295 | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Ribosomal protein S11 (rps11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.995 |
infC | rpsO | HP_0124 | HP_1040 | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Ribosomal protein S15 (rps15); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.977 |
infC | rpsZ | HP_0124 | HP_1306 | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Ribosomal protein S14 (rpS14); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. | 0.961 |
infC | thrS | HP_0124 | HP_0123 | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | threonyl-tRNA synthetase (thrS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.989 |
rplC | infC | HP_1319 | HP_0124 | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Translation initiation factor IF-3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 0.911 |
rplC | rplK | HP_1319 | HP_1202 | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L11 (rpl11); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.999 |
rplC | rplO | HP_1319 | HP_1301 | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L15 (rpl15); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.999 |
rplC | rplT | HP_1319 | HP_0126 | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L20 (rpl20); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | 0.995 |
rplC | rplV | HP_1319 | HP_1314 | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L22 (rpl22); This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.999 |
rplC | rpmF | HP_1319 | HP_0200 | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L32 (rpl32); Similar to SP:P07840 percent identity: 41.67; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL32 family. | 0.988 |
rplC | rpsK | HP_1319 | HP_1295 | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein S11 (rps11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.997 |
rplC | rpsO | HP_1319 | HP_1040 | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein S15 (rps15); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.994 |
rplC | rpsZ | HP_1319 | HP_1306 | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein S14 (rpS14); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. | 0.998 |
rplC | thrS | HP_1319 | HP_0123 | Ribosomal protein L3 (rpl3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | threonyl-tRNA synthetase (thrS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.964 |