STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccoPCytochrome c oxidase, diheme subunit, membrane-bound (fixP); C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. CcoP subunit is required for transferring electrons from donor cytochrome c via its heme groups to CcoO subunit. From there, electrons are shuttled to the catalytic binuclear center of CcoN subunit where oxygen reduction takes place. The complex also functions as a proton pump (By similarity). (286 aa)    
Predicted Functional Partners:
HP_0144
Cytochrome c oxidase, heme b and copper-binding subunit, membrane-bound (fixN); Similar to GB:Z21854 GB:X15079 SP:Q05572 PID:49408 percent identity: 43.88; identified by sequence similarity; putative; Belongs to the heme-copper respiratory oxidase family.
 
 0.999
HP_0145
Cytochrome c oxidase, monoheme subunit, membrane-bound (fixO); Similar to GB:L07487 PID:152200 percent identity: 45.66; identified by sequence similarity; putative.
 0.999
HP_1539
Ubiquinol cytochrome c oxidoreductase, cytochrome b subunit (fbcH); Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 0.998
HP_1540
Ubiquinol cytochrome c oxidoreductase, Rieske 2Fe-2S subunit (fbcF); Similar to GB:J03176 PID:152083 SP:P51130 percent identity: 39.22; identified by sequence similarity; putative.
 
 0.998
HP_0146
Cbb3-type cytochrome c oxidase subunit Q (CcoQ); Similar to GP:1377867 percent identity: 44.19; identified by sequence similarity; putative.
  
 0.997
HP_0407
Biotin sulfoxide reductase (bisC); Similar to GB:L42023 SP:P44798 PID:1005502 PID:1220726 PID:1204894 percent identity: 42.75; identified by sequence similarity; putative; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 0.979
HP_1508
Ferrodoxin-like protein; Similar to PID:1002882 percent identity: 29.38; identified by sequence similarity; putative.
 
  
 0.976
HP_0150
Predicted coding region HP0150; Hypothetical protein; identified by GeneMark; putative.
  
 
 0.972
tuf
Translation elongation factor EF-Tu (tufB); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.950
HP_1222
D-lactate dehydrogenase (dld); Similar to GB:L42023 PID:1006517 PID:1221287 PID:1205408 SP:Q57252 percent identity: 26.99; identified by sequence similarity; putative.
   
 0.942
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.