STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ndkNucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa)    
Predicted Functional Partners:
rpsO
Ribosomal protein S15 (rps15); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
  0.999
rpsG
Ribosomal protein S7 (rps7); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
  0.999
rpsL
Ribosomal protein S12 (rps12); With S4 and S5 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS12 family.
   
  0.999
rpsJ
Ribosomal protein S10 (rps10); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
  0.999
rpsB
Ribosomal protein S2 (rps2); Similar to GB:D26562 SP:P02351 GB:V00343 PID:42842 PID:473824 percent identity: 49.58; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
   
 0.999
rpsI
Ribosomal protein S9 (rps9); Similar to GB:X02130 SP:P02363 PID:535073 PID:606169 GB:U00096 percent identity: 50.39; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS9 family.
   
  0.998
rpsP
Ribosomal protein S16 (rpS16); Similar to GB:L42023 SP:P44382 PID:1003307 PID:1222122 PID:1204461 percent identity: 46.75; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS16 family.
  
  0.998
rpsF
Ribosomal protein S6 (rps6); Binds together with S18 to 16S ribosomal RNA; Belongs to the bacterial ribosomal protein bS6 family.
   
  0.998
rpsK
Ribosomal protein S11 (rps11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
   
  0.998
rpsZ
Ribosomal protein S14 (rpS14); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
   
  0.998
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.