STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HP_0312Conserved hypothetical ATP-binding protein; Similar to GP:953179 percent identity: 34.05; identified by sequence similarity; putative. (321 aa)    
Predicted Functional Partners:
HP_0311
Predicted coding region HP0311; Hypothetical protein; identified by GeneMark; putative.
   
   0.957
map
Methionine amino peptidase (map); Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
   
   0.873
rpsZ
Ribosomal protein S14 (rpS14); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
 
 0.808
pgdA
Conserved hypothetical protein; Catalyzes the N-deacetylation of peptidoglycan (PG), an important mechanism that appears to confer lysozyme resistance and to mitigate host immune detection; this likely contributes to pathogen persistence in the host. The exact nature of the residue in PG that is deacetylated has not been determined. Is also able to catalyze the deacetylation of acetylated xylan, and, to a lesser extent, that of chitin and chitosan. Therefore, this enzyme might play a role during infection, considering that xylan-containing carbohydrate structures are among those common [...]
 
     0.719
rpmB
Ribosomal protein L28 (rpL28); Similar to GB:L43967 SP:P47665 PID:1046142 percent identity: 41.67; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.673
HP_0309
Conserved hypothetical protein; Similar to PID:929801 SP:P55176 percent identity: 31.27; identified by sequence similarity; putative.
 
     0.670
rpmG
Ribosomal protein L33 (rpL33); Similar to SP:P23375 percent identity: 55.10; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL33 family.
  
  
 0.518
HP_0308
Predicted coding region HP0308; Hypothetical protein; identified by GeneMark; putative.
       0.439
hemL
Glutamate-1-semialdehyde 2,1-aminomutase (hemL); Similar to GB:D26562 SP:P23893 GB:X53696 PID:41621 PID:473813 percent identity: 51.30; identified by sequence similarity; putative.
       0.419
HP_0307
Predicted coding region HP0307; Hypothetical protein; identified by GeneMark; putative.
       0.419
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.