STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HP_0509Glycolate oxidase subunit (glcD); Similar to GP:1763300 percent identity: 98.01; identified by sequence similarity; putative. (459 aa)    
Predicted Functional Partners:
HP_0666
Anaerobic glycerol-3-phosphate dehydrogenase, subunit C (glpC); Similar to GB:M20938 SP:P13034 PID:146179 GB:U00096 PID:1788576 percent identity: 26.52; identified by sequence similarity; putative.
 
 0.996
HP_0096
Phosphoglycerate dehydrogenase; Similar to GB:L77117 PID:1591676 percent identity: 31.03; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.934
HP_0485
Catalase-like protein; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
   
  0.924
katA
Catalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
   
  0.924
HP_1099
2-keto-3-deoxy-6-phosphogluconate aldolase (eda); Similar to GB:L20897 GB:M87458 GB:X63694 GB:X68871 PID:145827 percent identity: 50.25; identified by sequence similarity; putative.
   
 
 0.923
ccoP
Cytochrome c oxidase, diheme subunit, membrane-bound (fixP); C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. CcoP subunit is required for transferring electrons from donor cytochrome c via its heme groups to CcoO subunit. From there, electrons are shuttled to the catalytic binuclear center of CcoN subunit where oxygen reduction takes place. The complex also functions as a proton pump (By similarity).
   
  0.885
HP_1360
4-hydroxybenzoate octaprenyltransferase (ubiA); Similar to SP:P26601 GB:M96268 GB:X57434 GB:X66619 GB:X69522 percent identity: 26.58; identified by sequence similarity; putative; Belongs to the UbiA prenyltransferase family.
    
 0.861
pgbA
Predicted coding region HP0508; Binds plasminogen, specifically, and in a concentration and lysine-dependent manner. Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin. Acquisition of plasminogen/plasmin could enable H.pylori to degrade host components.
    
  0.843
HP_0506
Conserved hypothetical secreted protein; Similar to GB:L42023 SP:P44693 PID:1003702 PID:1222338 PID:1204659 percent identity: 29.81; identified by sequence similarity; putative.
       0.825
HP_0507
Conserved hypothetical protein; Similar to GP:1262938 percent identity: 36.36; identified by sequence similarity; putative.
       0.825
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.