node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HP_0056 | HP_0690 | HP_0056 | HP_0690 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Acetyl coenzyme A acetyltransferase (thiolase) (fadA); Similar to GB:L42023 SP:P44873 PID:1005748 PID:1220864 PID:1205019 percent identity: 52.04; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. Thiolase family. | 0.689 |
HP_0056 | HP_0695 | HP_0056 | HP_0695 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Hydantoin utilization protein A (hyuA); Similar to SP:Q01262 PID:151282 PID:216831 percent identity: 28.57; identified by sequence similarity; putative. | 0.765 |
HP_0056 | HP_0696 | HP_0056 | HP_0696 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | N-methylhydantoinase; Similar to GB:L77117 PID:1591627 percent identity: 26.92; identified by sequence similarity; putative. | 0.747 |
HP_0056 | HP_1118 | HP_0056 | HP_1118 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Gamma-glutamyltranspeptidase (ggt); Similar to GB:M28722 SP:P18956 PID:146133 PID:466583 PID:606382 percent identity: 53.21; identified by sequence similarity; putative. | 0.947 |
HP_0056 | gdhA | HP_0056 | HP_0380 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.970 |
HP_0056 | gyrA | HP_0056 | HP_0701 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | DNA gyrase, sub A (gyrA); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.439 |
HP_0056 | sodB | HP_0056 | HP_0389 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Superoxide dismutase (sodB); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.450 |
HP_0690 | HP_0056 | HP_0690 | HP_0056 | Acetyl coenzyme A acetyltransferase (thiolase) (fadA); Similar to GB:L42023 SP:P44873 PID:1005748 PID:1220864 PID:1205019 percent identity: 52.04; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. Thiolase family. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.689 |
HP_0690 | HP_0695 | HP_0690 | HP_0695 | Acetyl coenzyme A acetyltransferase (thiolase) (fadA); Similar to GB:L42023 SP:P44873 PID:1005748 PID:1220864 PID:1205019 percent identity: 52.04; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. Thiolase family. | Hydantoin utilization protein A (hyuA); Similar to SP:Q01262 PID:151282 PID:216831 percent identity: 28.57; identified by sequence similarity; putative. | 0.554 |
HP_0690 | HP_0696 | HP_0690 | HP_0696 | Acetyl coenzyme A acetyltransferase (thiolase) (fadA); Similar to GB:L42023 SP:P44873 PID:1005748 PID:1220864 PID:1205019 percent identity: 52.04; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. Thiolase family. | N-methylhydantoinase; Similar to GB:L77117 PID:1591627 percent identity: 26.92; identified by sequence similarity; putative. | 0.519 |
HP_0690 | HP_0697 | HP_0690 | HP_0697 | Acetyl coenzyme A acetyltransferase (thiolase) (fadA); Similar to GB:L42023 SP:P44873 PID:1005748 PID:1220864 PID:1205019 percent identity: 52.04; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. Thiolase family. | Predicted coding region HP0697; Hypothetical protein; identified by GeneMark; putative. | 0.457 |
HP_0695 | HP_0056 | HP_0695 | HP_0056 | Hydantoin utilization protein A (hyuA); Similar to SP:Q01262 PID:151282 PID:216831 percent identity: 28.57; identified by sequence similarity; putative. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.765 |
HP_0695 | HP_0690 | HP_0695 | HP_0690 | Hydantoin utilization protein A (hyuA); Similar to SP:Q01262 PID:151282 PID:216831 percent identity: 28.57; identified by sequence similarity; putative. | Acetyl coenzyme A acetyltransferase (thiolase) (fadA); Similar to GB:L42023 SP:P44873 PID:1005748 PID:1220864 PID:1205019 percent identity: 52.04; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. Thiolase family. | 0.554 |
HP_0695 | HP_0696 | HP_0695 | HP_0696 | Hydantoin utilization protein A (hyuA); Similar to SP:Q01262 PID:151282 PID:216831 percent identity: 28.57; identified by sequence similarity; putative. | N-methylhydantoinase; Similar to GB:L77117 PID:1591627 percent identity: 26.92; identified by sequence similarity; putative. | 0.999 |
HP_0695 | HP_0697 | HP_0695 | HP_0697 | Hydantoin utilization protein A (hyuA); Similar to SP:Q01262 PID:151282 PID:216831 percent identity: 28.57; identified by sequence similarity; putative. | Predicted coding region HP0697; Hypothetical protein; identified by GeneMark; putative. | 0.998 |
HP_0695 | HP_0698 | HP_0695 | HP_0698 | Hydantoin utilization protein A (hyuA); Similar to SP:Q01262 PID:151282 PID:216831 percent identity: 28.57; identified by sequence similarity; putative. | Predicted coding region HP0698; Hypothetical protein; identified by GeneMark; putative. | 0.509 |
HP_0695 | HP_1118 | HP_0695 | HP_1118 | Hydantoin utilization protein A (hyuA); Similar to SP:Q01262 PID:151282 PID:216831 percent identity: 28.57; identified by sequence similarity; putative. | Gamma-glutamyltranspeptidase (ggt); Similar to GB:M28722 SP:P18956 PID:146133 PID:466583 PID:606382 percent identity: 53.21; identified by sequence similarity; putative. | 0.442 |
HP_0695 | dgkA | HP_0695 | HP_0700 | Hydantoin utilization protein A (hyuA); Similar to SP:Q01262 PID:151282 PID:216831 percent identity: 28.57; identified by sequence similarity; putative. | Diacylglycerol kinase (dgkA); Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | 0.430 |
HP_0695 | gdhA | HP_0695 | HP_0380 | Hydantoin utilization protein A (hyuA); Similar to SP:Q01262 PID:151282 PID:216831 percent identity: 28.57; identified by sequence similarity; putative. | Glutamate dehydrogenase (gdhA); Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.466 |
HP_0696 | HP_0056 | HP_0696 | HP_0056 | N-methylhydantoinase; Similar to GB:L77117 PID:1591627 percent identity: 26.92; identified by sequence similarity; putative. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.747 |