node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HP_0735 | guaA | HP_0735 | HP_0409 | Xanthine guanine phosphoribosyl transferase (gpt); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 27.12; identified by sequence similarity; putative. | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | 0.923 |
HP_0735 | guaB | HP_0735 | HP_0829 | Xanthine guanine phosphoribosyl transferase (gpt); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 27.12; identified by sequence similarity; putative. | Inosine-5'-monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.944 |
HP_0735 | purA | HP_0735 | HP_0255 | Xanthine guanine phosphoribosyl transferase (gpt); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 27.12; identified by sequence similarity; putative. | Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.543 |
HP_0735 | surE | HP_0735 | HP_0930 | Xanthine guanine phosphoribosyl transferase (gpt); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 27.12; identified by sequence similarity; putative. | Stationary-phase survival protein (surE); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.917 |
HP_1030 | HP_1119 | HP_1030 | HP_1119 | fliY protein (fliY); Similar to GB:M86738 SP:P24073 PID:142926 PID:551704 GB:AL009126 percent identity: 29.27; identified by sequence similarity; putative. | Flagellar hook-associated protein 1 (HAP1) (flgK); Similar to GB:X51738 SP:P15932 GB:X52093 PID:47679 percent identity: 27.56; identified by sequence similarity; putative. | 0.999 |
HP_1030 | fliD | HP_1030 | HP_0752 | fliY protein (fliY); Similar to GB:M86738 SP:P24073 PID:142926 PID:551704 GB:AL009126 percent identity: 29.27; identified by sequence similarity; putative. | Flagellar hook-associated protein 2 (fliD); Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential to colonize and establish infection in gastric mucosa as a result of its essential role in motility. Has effect on flaA gene transcription. | 0.975 |
HP_1030 | guaB | HP_1030 | HP_0829 | fliY protein (fliY); Similar to GB:M86738 SP:P24073 PID:142926 PID:551704 GB:AL009126 percent identity: 29.27; identified by sequence similarity; putative. | Inosine-5'-monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.944 |
HP_1119 | HP_1030 | HP_1119 | HP_1030 | Flagellar hook-associated protein 1 (HAP1) (flgK); Similar to GB:X51738 SP:P15932 GB:X52093 PID:47679 percent identity: 27.56; identified by sequence similarity; putative. | fliY protein (fliY); Similar to GB:M86738 SP:P24073 PID:142926 PID:551704 GB:AL009126 percent identity: 29.27; identified by sequence similarity; putative. | 0.999 |
HP_1119 | fliD | HP_1119 | HP_0752 | Flagellar hook-associated protein 1 (HAP1) (flgK); Similar to GB:X51738 SP:P15932 GB:X52093 PID:47679 percent identity: 27.56; identified by sequence similarity; putative. | Flagellar hook-associated protein 2 (fliD); Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential to colonize and establish infection in gastric mucosa as a result of its essential role in motility. Has effect on flaA gene transcription. | 0.981 |
HP_1119 | guaB | HP_1119 | HP_0829 | Flagellar hook-associated protein 1 (HAP1) (flgK); Similar to GB:X51738 SP:P15932 GB:X52093 PID:47679 percent identity: 27.56; identified by sequence similarity; putative. | Inosine-5'-monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.939 |
fliD | HP_1030 | HP_0752 | HP_1030 | Flagellar hook-associated protein 2 (fliD); Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential to colonize and establish infection in gastric mucosa as a result of its essential role in motility. Has effect on flaA gene transcription. | fliY protein (fliY); Similar to GB:M86738 SP:P24073 PID:142926 PID:551704 GB:AL009126 percent identity: 29.27; identified by sequence similarity; putative. | 0.975 |
fliD | HP_1119 | HP_0752 | HP_1119 | Flagellar hook-associated protein 2 (fliD); Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential to colonize and establish infection in gastric mucosa as a result of its essential role in motility. Has effect on flaA gene transcription. | Flagellar hook-associated protein 1 (HAP1) (flgK); Similar to GB:X51738 SP:P15932 GB:X52093 PID:47679 percent identity: 27.56; identified by sequence similarity; putative. | 0.981 |
fliD | guaB | HP_0752 | HP_0829 | Flagellar hook-associated protein 2 (fliD); Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential to colonize and establish infection in gastric mucosa as a result of its essential role in motility. Has effect on flaA gene transcription. | Inosine-5'-monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.939 |
guaA | HP_0735 | HP_0409 | HP_0735 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | Xanthine guanine phosphoribosyl transferase (gpt); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 27.12; identified by sequence similarity; putative. | 0.923 |
guaA | guaB | HP_0409 | HP_0829 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purA | HP_0409 | HP_0255 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.889 |
guaA | purB | HP_0409 | HP_1112 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase (purB); Similar to GB:J02732 SP:P12047 PID:143366 GB:AL009126 percent identity: 49.53; identified by sequence similarity; putative. | 0.936 |
guaA | rpoBC | HP_0409 | HP_1198 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase, beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.923 |
guaA | surE | HP_0409 | HP_0930 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | Stationary-phase survival protein (surE); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.973 |
guaB | HP_0735 | HP_0829 | HP_0735 | Inosine-5'-monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Xanthine guanine phosphoribosyl transferase (gpt); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 27.12; identified by sequence similarity; putative. | 0.944 |