STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HP_0837Predicted coding region HP0837; Hypothetical protein; identified by GeneMark; putative. (102 aa)    
Predicted Functional Partners:
HP_0836
Predicted coding region HP0836; Hypothetical protein; identified by GeneMark; putative.
  
   0.960
HP_0295
Flagellin B homolog (fla); Similar to GB:L08907 SP:Q07911 PID:305389 GB:AE000511 PID:2313197 percent identity: 32.90; identified by sequence similarity; putative.
  
  
 0.845
pseB
flaA1 protein; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose.
  
  
 0.773
HP_0838
Predicted coding region HP0838; Hypothetical protein; identified by GeneMark; putative.
       0.771
HP_0839
Outer membrane protein P1 (ompP1); Similar to GB:M73494 percent identity: 23.27; identified by sequence similarity; putative.
       0.770
HP_0841
Pantothenate metabolism flavoprotein (dfp); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
       0.748
HP_0842
Predicted coding region HP0842; Hypothetical protein; identified by GeneMark; putative.
       0.748
HP_1119
Flagellar hook-associated protein 1 (HAP1) (flgK); Similar to GB:X51738 SP:P15932 GB:X52093 PID:47679 percent identity: 27.56; identified by sequence similarity; putative.
  
    0.724
flaB
Flagellin B (flaB); Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Important for motility and virulence.
  
  
 0.723
fliD
Flagellar hook-associated protein 2 (fliD); Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential to colonize and establish infection in gastric mucosa as a result of its essential role in motility. Has effect on flaA gene transcription.
  
    0.720
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.