Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HP_0905Phosphotransacetylase (pta); Similar to SP:P39184 GB:U00096 PID:1359438 PID:1788635 PID:1799670 percent identity: 29.46; identified by sequence similarity; putative. (223 aa)    
Predicted Functional Partners:
tal
Transaldolase (tal); Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
   
 
 0.746
fumC
Fumarase (fumC); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.680
alaS
alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.679
gltA
Citrate synthase (gltA); Similar to SP:P09948 GB:U14334 GB:U20244 PID:152472 PID:540095 percent identity: 47.78; identified by sequence similarity; putative.
  
 
 0.642
HP_0056
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 0.634
icd
Isocitrate dehydrogenase (icd); Similar to GB:J02799 SP:P08200 PID:146432 GB:U00096 PID:1651560 percent identity: 70.73; identified by sequence similarity; putative; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.604
acsA
acetyl-CoA synthetase (acoE); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 0.594
rpoBC
DNA-directed RNA polymerase, beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.577
frdA
Fumarate reductase, flavoprotein subunit (frdA); Similar to SP:P17412 PID:48513 PID:2281999 percent identity: 69.41; identified by sequence similarity; putative.
  
  
 0.561
HP_1110
Pyruvate ferredoxin oxidoreductase, alpha subunit; Similar to PID:1197363 percent identity: 41.03; identified by sequence similarity; putative.
     
 0.536
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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