Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HP_0908Flagellar hook (flgE); Similar to PID:600724 SP:P50610 GB:AE000511 PID:2313997 PID:600725 percent identity: 29.39; identified by sequence similarity; putative. (605 aa)    
Predicted Functional Partners:
HP_0907
Hook assembly protein, flagella (flgD); Required for flagellar hook formation. May act as a scaffolding protein.
 
 
 0.984
HP_1558
Flagellar basal-body rod protein (flgC); Proximal rod protein; similar to PID:1165277 PID:1196316 SP:Q57466 GB:AE000783 percent identity: 46.04; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
 
 
 0.981
HP_1030
fliY protein (fliY); Similar to GB:M86738 SP:P24073 PID:142926 PID:551704 GB:AL009126 percent identity: 29.27; identified by sequence similarity; putative.
 
 
 0.977
fliG
Flagellar motor switch protein (fliG); One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Required for flagellum synthesis and motility. In H.pylori four flagellar switch proteins are encoded, FliG, FliM, FliN and FliY.
 
 
 0.969
HP_0351
Flagellar basal-body M-ring protein (fliF); The M ring may be actively involved in energy transduction. Belongs to the FliF family.
 
 
 0.960
HP_0685
Flagellar biosynthetic protein (fliP); Similar to GB:M87005 SP:P35528 PID:142931 GB:AL009126 percent identity: 50.92; identified by sequence similarity; putative.
 
 
 0.944
HP_1031
Flagellar motor switch protein (fliM); Similar to PID:1165263 PID:1185056 GB:AE000783 percent identity: 34.41; identified by sequence similarity; putative.
 
 
 0.937
flhB
Flagellar biosynthetic protein (flhB); Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity); Belongs to the type III secretion exporter family.
 
 
 0.933
flgE
Flagellar hook (flgE); A flexible structure which links the flagellar filament to the drive apparatus in the basal body. Absence of the gene leads to absence of the hook protein, lack of the flagellar filament and thus loss of mobility. Approximately wild-type levels of the flagellar subunits are still produced and accumulate mostly in the cytosol.
  
  
 
0.929
flgI
Flagellar basal-body P-ring protein (flgI); Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
 
 0.926
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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