STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppkPolyphosphate kinase (ppk); Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family. (675 aa)    
Predicted Functional Partners:
HP_0278
Guanosine pentaphosphate phosphohydrolase (gppA); Similar to GB:M87049 SP:P25552 GB:M83316 PID:148183 PID:146252 percent identity: 26.30; identified by sequence similarity; putative.
 
  
 0.960
ppa
Inorganic pyrophosphatase (ppa); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
   
 
 0.947
pyrD
Dihydroorotate dehydrogenase (pyrD); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
    0.758
HP_1012
Protease (pqqE); Similar to PID:1161059 percent identity: 29.64; identified by sequence similarity; putative; Belongs to the peptidase M16 family.
       0.750
dapA
Dihydrodipicolinate synthetase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
       0.729
HP_1014
7-alpha-hydroxysteroid dehydrogenase (hdhA); Similar to GB:D10497 SP:P25529 PID:868018 PID:912437 GB:U00096 percent identity: 33.07; identified by sequence similarity; putative.
       0.729
HP_1016
Phosphatidylglycerophosphate synthase (pgsA); Similar to GB:M12299 SP:P06978 PID:473749 GB:U00096 PID:1736571 percent identity: 35.37; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.589
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
  
  
 0.544
dnaK
Chaperone and heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
     
 0.532
HP_1491
Phosphate permease; Potential transporter for phosphate; Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
  
  
 0.456
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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