STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsHCell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins. (632 aa)    
Predicted Functional Partners:
HP_0248
Conserved hypothetical protein; Similar to GP:1652146 percent identity: 30.71; identified by sequence similarity; putative.
   
 0.896
prmA
Ribosomal protein L11 methyltransferase (prmA); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
     
 0.846
folE
GTP cyclohydrolase I (folE); Similar to PID:757796 SP:P51594 percent identity: 50.87; identified by sequence similarity; putative.
 
    0.841
copP
Copper ion binding protein (copP); Part of a cation-transporting system which is associated with copper export out of the H.pylori cells.
     
 0.831
pssA
Phosphatidylserine synthase (pssA); Similar to GP:1477770 percent identity: 99.58; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.818
copA
Copper-transporting ATPase, P-type (copA); Probably involved in copper export.
       0.817
cheY1
Chemotaxis protein (cheY); Chemotactic response regulator protein that modulates the rotation direction of bacterial flagellar motors. Plays an important role in the colonization and infection of Helicobacter pylori. Upon phosphorylation by CheA, interacts with the flagellar motor protein FliM to cause clockwise flagellar rotation and bacterial reversals, as opposed to straight swimming when CheY1 is not phosphorylated.
       0.814
rpsA
Ribosomal protein S1 (rps1); Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
  
   0.791
clpX
ATP-dependent protease ATPase subunit (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
   
  
 0.785
HP_1070
Predicted coding region HP1070; Hypothetical protein; identified by GeneMark; putative.
       0.773
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.