STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsHCell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins. (632 aa)    
Predicted Functional Partners:
HP_0248
Conserved hypothetical protein; Similar to GP:1652146 percent identity: 30.71; identified by sequence similarity; putative.
   
 0.990
rplO
Ribosomal protein L15 (rpl15); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.900
rplM
Ribosomal protein L13 (rpl13); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.892
rpmA
Ribosomal protein L27 (rpl27); Similar to GB:L42023 SP:P44363 PID:1005959 PID:1220982 PID:1205126 percent identity: 64.71; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.890
rplQ
Ribosomal protein L17 (rpl17); Similar to GB:L42023 SP:P44355 PID:1005810 PID:1220898 PID:1205052 percent identity: 48.28; identified by sequence similarity; putative.
   
 
 0.890
rpsG
Ribosomal protein S7 (rps7); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
   0.886
rplB
Ribosomal protein L2 (rpl2); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.886
rpsK
Ribosomal protein S11 (rps11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
   
   0.885
rpsP
Ribosomal protein S16 (rpS16); Similar to GB:L42023 SP:P44382 PID:1003307 PID:1222122 PID:1204461 percent identity: 46.75; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS16 family.
   
   0.884
rpmJ
Ribosomal protein L36 (rpl36); Similar to SP:P21194 GB:M12432 PID:42990 PID:606233 PID:1128970 percent identity: 81.58; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL36 family.
   
   0.884
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.