STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parBPlasmid replication-partition related protein; Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity). (290 aa)    
Predicted Functional Partners:
HP_1139
SpoOJ regulator (soj); Similar to GB:D26185 SP:P37522 PID:467381 PID:580906 GB:AL009126 percent identity: 47.41; identified by sequence similarity; putative.
 
 0.999
fmt
methionyl-tRNA formyltransferase (fmt); Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
  
 0.899
HP_1000
PARA protein; Similar to SP:P07175 GB:X05121 PID:142267 PID:39112 percent identity: 29.73; identified by sequence similarity; putative.
  
 
 0.874
HP_1140
Biotin operon repressor/biotin acetyl coenzyme A carboxylase synthetase (birA); Similar to SP:P06709 GB:L14557 GB:M10123 GB:M15820 PID:145432 percent identity: 36.94; identified by sequence similarity; putative.
  
    0.838
rsmG
Glucose-inhibited division protein (gidB); Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
  
  
 0.808
HP_1142
Predicted coding region HP1142; Hypothetical protein; identified by GeneMark; putative.
  
  
 0.791
dnaA
Chromosomal replication initiator protein (dnaA); Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).
 
  
 0.736
ftsK
Cell division protein (ftsK); Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DN [...]
  
  
 0.725
atpF
ATP synthase F0, subunit b (atpF); F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
    0.666
HP_1137
ATP synthase F0, subunit b' (atpF'); Similar to SP:Q05367 PID:49216 percent identity: 32.52; identified by sequence similarity; putative; Belongs to the ATPase B chain family.
  
    0.660
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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