STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HP_1223Predicted coding region HP1223; Hypothetical protein; identified by GeneMark; putative. (110 aa)    
Predicted Functional Partners:
sodB
Superoxide dismutase (sodB); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.948
rpsQ
Ribosomal protein S17 (rps17); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.940
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
    
   0.939
rplU
Ribosomal protein L21 (rpl21); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
   0.927
rplQ
Ribosomal protein L17 (rpl17); Similar to GB:L42023 SP:P44355 PID:1005810 PID:1220898 PID:1205052 percent identity: 48.28; identified by sequence similarity; putative.
   
   0.927
HP_0813
Conserved hypothetical protein; Similar to GB:U00011 PID:466827 SP:Q49649 percent identity: 32.47; identified by sequence similarity; putative.
  
 0.919
rplK
Ribosomal protein L11 (rpl11); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
   0.919
rplM
Ribosomal protein L13 (rpl13); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.918
rplX
Ribosomal protein L24 (rpl24); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
   0.908
rplO
Ribosomal protein L15 (rpl15); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.907
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.