STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bamDCompetence lipoprotein (comL); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (220 aa)    
Predicted Functional Partners:
bamA
Protective surface antigen D15; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
 
 0.987
HP_1498
Predicted coding region HP1498; Hypothetical protein; identified by GeneMark; putative.
  
   
 0.844
HP_1089
Predicted coding region HP1089; Hypothetical protein; identified by GeneMark; putative.
 
     0.802
HP_0499
Phospholipase A1 precursor (DR-phospholipase A); Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.
    
   0.779
pgbB
Predicted coding region HP0863; Binds plasminogen, specifically, and in a concentration and lysine-dependent manner. Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin. Acquisition of plasminogen/plasmin could enable H.pylori to degrade host components.
  
     0.774
HP_1042
Predicted coding region HP1042; Hydrolyzes cAMP to 5'-AMP and cGMP to 5'-GMP. Does not show phosphohydrolase activity toward various phosphatidylcholine and phosphorylated sugars.
  
    0.774
HP_1361
Competence locus E (comE3); Similar to GB:L15202 SP:P39695 PID:289262 PID:1303798 GB:AL009126 percent identity: 27.47; identified by sequence similarity; putative.
 
   
 0.762
tolB
Colicin tolerance-like protein (tolB); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
   
 0.760
HP_1451
Predicted coding region HP1451; Hypothetical protein; identified by GeneMark; putative.
  
     0.760
gatC
Glu-tRNA(Gln) amidotransferase, subunit C (gatC); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity); Belongs to the GatC family.
  
     0.759
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.