STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDSialoglycoprotease (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (340 aa)    
Predicted Functional Partners:
HP_1051
Predicted coding region HP1051; Hypothetical protein; identified by GeneMark; putative.
  
 
 0.983
HP_0716
Conserved hypothetical protein; Similar to GB:L42023 SP:P44492 PID:1003034 PID:1221973 PID:1204323 percent identity: 30.21; identified by sequence similarity; putative.
  
 
 0.961
gltX2
glutamyl-tRNA synthetase (gltX); Aminoacylates tRNA(Gln) with glutamate. Does not aminoacylate tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
   
 0.649
aroB
3-dehydroquinate synthase (aroB); Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
      0.641
serS
seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
  
 0.605
rsmA
16S rRNA (adenosine-N6,N6-)-dimethyltransferase (ksgA); Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.590
gltX1
glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
   
 0.585
gpsA
Glycerol-3-phosphate dehydrogenase, NAD(P)+ dependent; Similar to SP:P46919 PID:974332 PID:1146220 GB:AL009126 percent identity: 36.22; identified by sequence similarity; putative; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
      0.585
leuS
leucyl-tRNA synthetase (leuS); Similar to GB:L42023 SP:P43827 PID:1006043 PID:1221027 PID:1205168 percent identity: 45.93; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.583
pdxA
Pyridoxal phosphate biosynthetic protein A (pdxA); Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
  
    0.583
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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