| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hemD | holA | BVAF_583 | BVAF_314 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | DNA polymerase III, delta subunit. | 0.746 |
| hemD | holD | BVAF_583 | BVAF_111 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.652 |
| hemD | lpp | BVAF_583 | BVAF_367 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Major outer membrane lipoprotein. | 0.713 |
| hemD | lptC | BVAF_583 | BVAF_044 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Conserved hypothetical protein; Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Belongs to the LptC family. | 0.688 |
| hemD | omp | BVAF_583 | BVAF_476 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Outer membrane protein. | 0.658 |
| hemD | rlpB | BVAF_583 | BVAF_315 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hypothetical protein. | 0.675 |
| hemD | smpA | BVAF_583 | BVAF_548 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Small protein A. | 0.727 |
| hemD | tolA | BVAF_583 | BVAF_339 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | tolA domain protein. | 0.643 |
| hemD | yeeX | BVAF_583 | BVAF_461 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Conserved hypothetical protein; Belongs to the UPF0265 family. | 0.635 |
| hemD | yhcB | BVAF_583 | BVAF_048 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Conserved hypothetical protein. | 0.674 |
| holA | hemD | BVAF_314 | BVAF_583 | DNA polymerase III, delta subunit. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.746 |
| holA | holD | BVAF_314 | BVAF_111 | DNA polymerase III, delta subunit. | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.998 |
| holA | lpp | BVAF_314 | BVAF_367 | DNA polymerase III, delta subunit. | Major outer membrane lipoprotein. | 0.476 |
| holA | lptC | BVAF_314 | BVAF_044 | DNA polymerase III, delta subunit. | Conserved hypothetical protein; Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Belongs to the LptC family. | 0.697 |
| holA | omp | BVAF_314 | BVAF_476 | DNA polymerase III, delta subunit. | Outer membrane protein. | 0.704 |
| holA | rlpB | BVAF_314 | BVAF_315 | DNA polymerase III, delta subunit. | Hypothetical protein. | 0.893 |
| holA | smpA | BVAF_314 | BVAF_548 | DNA polymerase III, delta subunit. | Small protein A. | 0.699 |
| holA | tolA | BVAF_314 | BVAF_339 | DNA polymerase III, delta subunit. | tolA domain protein. | 0.604 |
| holA | yeeX | BVAF_314 | BVAF_461 | DNA polymerase III, delta subunit. | Conserved hypothetical protein; Belongs to the UPF0265 family. | 0.646 |
| holA | yhcB | BVAF_314 | BVAF_048 | DNA polymerase III, delta subunit. | Conserved hypothetical protein. | 0.728 |