STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahpCPeroxiredoxin, AhpC-TSA family. (199 aa)    
Predicted Functional Partners:
trxB
Thioredoxin reductase.
  
 
 0.928
zur
Zinc uptake regulation protein; Belongs to the Fur family.
  
  
 0.698
trxA
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.677
sodA
Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.641
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.639
groEL
60 kDa chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 0.591
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.542
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.510
lepB
Signal peptidase I; Belongs to the peptidase S26 family.
   
  
 0.504
lpdA
Dihydrolipoyl dehydrogenase.
   
 
 0.487
Your Current Organism:
Blochmannia vafer
NCBI taxonomy Id: 859654
Other names: C. Blochmannia vafer str. BVAF, Candidatus Blochmannia vafer BVAF, Candidatus Blochmannia vafer str. BVAF, Candidatus Blochmannia vafer strain BVAF
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.