STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grxDGlutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily. (110 aa)    
Predicted Functional Partners:
nfuA
Fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.857
ribE
Riboflavin synthase, alpha subunit.
  
    0.615
thrS
threonyl-tRNA synthetase.
  
 
 0.591
sufA
FeS cluster assembly protein sufA; Belongs to the HesB/IscA family.
  
 0.584
hisI
Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family.
     
 0.570
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
 
  
 0.545
erpA
Iron sulfur cluster insertion protein; Required for insertion of 4Fe-4S clusters for at least IspG.
   
 0.532
yrbA
bolA-like protein; Belongs to the BolA/IbaG family.
   
 
 0.519
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase.
  
     0.486
grxC
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
 
 0.460
Your Current Organism:
Blochmannia vafer
NCBI taxonomy Id: 859654
Other names: C. Blochmannia vafer str. BVAF, Candidatus Blochmannia vafer BVAF, Candidatus Blochmannia vafer str. BVAF, Candidatus Blochmannia vafer strain BVAF
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.