| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| folP | pabC | BVAF_099 | BVAF_405 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Aminodeoxychorismate lyase. | 0.913 |
| folP | thrA | BVAF_099 | BVAF_112 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Bifunctional aspartokinase/homoserine dehydrogenase 1; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.628 |
| folP | trpG | BVAF_099 | BVAF_428 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Glutamine amidotransferase. | 0.490 |
| hisI | ilvD | BVAF_470 | BVAF_592 | Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.655 |
| hisI | leuA | BVAF_470 | BVAF_134 | Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.574 |
| hisI | pabA | BVAF_470 | BVAF_570 | Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family. | Para-aminobenzoate synthase glutamine amidotransferase component II. | 0.410 |
| hisI | pabB | BVAF_470 | BVAF_444 | Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family. | Para-aminobenzoate synthase component 1. | 0.402 |
| hisI | pabC | BVAF_470 | BVAF_405 | Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family. | Aminodeoxychorismate lyase. | 0.694 |
| hisI | pheA | BVAF_470 | BVAF_180 | Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family. | Prephenate dehydratase. | 0.645 |
| hisI | thrA | BVAF_470 | BVAF_112 | Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family. | Bifunctional aspartokinase/homoserine dehydrogenase 1; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.868 |
| hisI | trpG | BVAF_470 | BVAF_428 | Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family. | Glutamine amidotransferase. | 0.816 |
| ilvD | hisI | BVAF_592 | BVAF_470 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family. | 0.655 |
| ilvD | leuA | BVAF_592 | BVAF_134 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.982 |
| ilvD | pabC | BVAF_592 | BVAF_405 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Aminodeoxychorismate lyase. | 0.707 |
| ilvD | pheA | BVAF_592 | BVAF_180 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Prephenate dehydratase. | 0.639 |
| ilvD | thrA | BVAF_592 | BVAF_112 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Bifunctional aspartokinase/homoserine dehydrogenase 1; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.806 |
| ilvD | trpG | BVAF_592 | BVAF_428 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Glutamine amidotransferase. | 0.583 |
| leuA | hisI | BVAF_134 | BVAF_470 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family. | 0.574 |
| leuA | ilvD | BVAF_134 | BVAF_592 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.982 |
| leuA | pabC | BVAF_134 | BVAF_405 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Aminodeoxychorismate lyase. | 0.695 |