STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCUnannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (382 aa)    
Predicted Functional Partners:
CQY22_011285
Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.990
serB
Unannotated protein.
 
 
 0.983
CQY22_009450
Unannotated protein; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 0.927
CQY22_000680
Unannotated protein.
 
 
 0.891
CQY22_018410
Unannotated protein.
  
 
 0.890
CQY22_003925
Unannotated protein.
 
 
 0.833
CQY22_011545
Unannotated protein.
 
 
 0.818
glyA
Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.749
CQY22_008415
Unannotated protein.
  
 
 0.745
dapD
Unannotated protein; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
  
 
 0.741
Your Current Organism:
Mycolicibacterium brumae
NCBI taxonomy Id: 85968
Other names: ATCC 51384, CCUG 37586, CIP 103465, DSM 44177, JCM 12273, M. brumae, Mycobacterium brumae, strain CR-270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.