STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metEUnannotated protein; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (754 aa)    
Predicted Functional Partners:
CQY22_015305
Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.979
metK
Unannotated protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.973
CQY22_014245
Unannotated protein; Belongs to the methylenetetrahydrofolate reductase family.
 
 0.972
CQY22_016055
Unannotated protein.
  
 0.956
CQY22_003915
Unannotated protein.
  
 
 0.955
ahcY
Unannotated protein; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.951
CQY22_009160
Unannotated protein.
  
 
 0.946
CQY22_011390
Unannotated protein.
  
 
 0.939
metZ
Unannotated protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 
 0.939
CQY22_003925
Unannotated protein.
    
 0.925
Your Current Organism:
Mycolicibacterium brumae
NCBI taxonomy Id: 85968
Other names: ATCC 51384, CCUG 37586, CIP 103465, DSM 44177, JCM 12273, M. brumae, Mycobacterium brumae, strain CR-270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.