STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEK22180.1Short=PGDH; Formate/glycerate dehydrogenase catalytic domain-like (SSF52283); D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (PF00389); D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (PF02826); NAD(P)-binding domain (G3DSA:3.40.50.720); 2-HYDROXYACID DEHYDROGENASE (PTHR10996); D-3-phosphogylcerate Dehydrogenase (PTHR10996:SF20); NAD(P)-binding domain (SSF51735); Protein involved in catalytic activity, binding, phosphoglycerate dehydrogenase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, cofactor binding, NAD [...] (314 aa)    
Predicted Functional Partners:
serC
Phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 0.971
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.937
AEK22321.1
Short=PGDH; Formate/glycerate dehydrogenase catalytic domain-like (SSF52283); D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (PF00389); NAD(P)-binding domain (G3DSA:3.40.50.720); D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (PF02826); 2-HYDROXYACID DEHYDROGENASE (PTHR10996); D-3-phosphogylcerate Dehydrogenase (PTHR10996:SF20); D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (PS00065); NAD(P)-binding domain (SSF51735); Protein involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, cofactor binding, NAD [...]
  
  
 
0.926
AEK22179.1
Probable macrolide-specific efflux protein macA; N-terminus: SpI(SignalPHMM); Flags: Precursor; 1 transmembrane domain; Secretion protein HlyD (TIGR01730); HlyD-like secretion proteins (Pfam 00529) (SSF111369); Secretion protein HlyD (PF00529); Protein involved in protein transporter activity and protein secretion; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
    0.778
AEK24069.1
N-terminus: TMH(LipoP); AltName: Full=Homoserine O-trans-acetylase;Short=Homoserine transacetylase;Short=HTA; 1 transmembrane domain; Alpha/beta hydrolase fold-1 (PF00561); alpha/beta-Hydrolases (SSF53474).
  
 
 0.686
AEK24070.1
Putative homoserine O-acetyltransferase; Weak similarity to UniProt:Q73UB0.
  
 
 0.686
AEK23081.1
AltName: Full=Uridine monophosphokinase;AltName: Full=Cytidine monophosphokinase; Undefined Gene3D domain (G3DSA:3.40.50.300); P-loop containing nucleoside triphosphate hydrolases (SSF52540); URIDINE KINASE RELATED (PTHR10285); Uridine kinase (PTHR10285:SF6); Uridine kinase (PR00988); PRK (PF00485); Uridine kinase (TIGR00235); Protein involved in ATP binding and phosphotransferase activity, alcohol group as acceptor.
   
  0.667
AEK22178.1
Conserved hypothetical protein; N-terminus: SpI(LipoP); 1 transmembrane domain; Integral outer membrane protein TolC, efflux pump component (SSF56954); Outer membrane efflux protein (PF02321); Protein involved in transporter activity and transport.
       0.658
AEK24068.1
AltName: Full=Aspartokinase I/homoserine dehydrogenase I;Short=AKI-HDI;Includes:RecName: Full=Aspartokinase;Includes:RecName: Full=Homoserine dehydrogenase; Aspartate/glutamate/uridylate kinase (SSF53633); NAD(P)-binding domain (G3DSA:3.40.50.720); Homoserine dehydrogenase, conserved site (PS01042); Amino acid-binding ACT (PF01842); Homoserine dehydrogenase, catalytic (PF00742); Aspartate/glutamate/uridylate kinase (G3DSA:3.40.1160.10); Bifunctional aspartokinase/homoserine dehydrogenase I (PIRSF000727); Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (SSF55347); Aspar [...]
  
 
 0.638
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.542
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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