STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
AEK22369.1Putative chloride channel protein clcB-like protein; N-terminus: TMH(LipoP); 10 transmembrane domains; Chloride channel, voltage gated (PF00654); Cystathionine (SM00116); Cystathionine beta-synthase, core (PS51371); VOLTAGE-GATED CLC-TYPE CHLORIDE CHANNEL ERIC (PTHR11689:SF14); Chloride channel, voltage gated (PR00762); CBS-domain (SSF54631); Chloride channel, core (G3DSA:1.10.3080.10); Cystathionine beta-synthase, core (PF00571); Chloride channel, core (SSF81340); Chloride channel, voltage gated (PTHR11689); Protein involved in voltage-gated chloride channel activity, ion channel acti [...] (598 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.868
AEK22154.1
Hypothetical protein; Putative endonuclease, Z1 domain (PF10593); P-loop containing nucleoside triphosphate hydrolases (SSF52540); Restriction endonuclease, type I, R subunit/Type III, Res subunit (PF04851); Protein involved in DNA binding, ATP binding and hydrolase activity.
   
 0.814
adk
ATP-AMP transphosphorylase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
  
 0.750
purL
Formylglycinamide ribotide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.733
ribB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
  
 0.663
AEK22543.1
Uncharacterized transporter yfbS; N-terminus: TMH(LipoP); 11 transmembrane domains; CATION TRANSPORTER RELATED (PTHR10283); Regulator of K+ conductance, C-terminal (PS51202); SODIUM/SULFATE TRANSPORTER (PTHR10283:SF12); Regulator of K+ conductance, C-terminal (PF02080); Divalent ion symporter (PF03600); NAD(P)-binding domain (SSF51735); Protein involved in citrate transmembrane transporter activity, cation transmembrane transporter activity, catalytic activity, binding, citrate transport, transmembrane transport, potassium ion transport and metabolic process.
  
  
 0.645
AEK24069.1
N-terminus: TMH(LipoP); AltName: Full=Homoserine O-trans-acetylase;Short=Homoserine transacetylase;Short=HTA; 1 transmembrane domain; Alpha/beta hydrolase fold-1 (PF00561); alpha/beta-Hydrolases (SSF53474).
  
  
 0.645
AEK24070.1
Putative homoserine O-acetyltransferase; Weak similarity to UniProt:Q73UB0.
  
  
 0.645
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.638
msrA-2
Peptide-methionine (R)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.612
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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